Imagine a game of chess where your opponent's king is in check. It cannot move, but the game is not over—the piece remains on the board. This is how the body might control HIV on its own: The virus would be contained and ...
Mar 23, 2026
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When our body fights an infection, the immune system must quickly activate defenses and trigger a beneficial inflammatory response. But it is just as important to resolve that inflammation and return to homeostasis. Macrophages ...
Jan 28, 2026
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In a preclinical study from Mass General Brigham, researchers have found that even short-term exposure to high levels of dietary fat results in a quick and selective loss of critical gut immune cells called ILC3s, promoting ...
Apr 6, 2026
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One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics ...
Feb 5, 2026
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Since scientists first discovered that human immune cells could be modified to become cancer-fighting agents, they've been trying to engineer a cell that's effective against solid tumors, which account for the vast majority ...
Feb 25, 2026
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People who live with obesity are "tagging" a memory of being overweight on a key part of the immune system—leaving people with ongoing risk of obesity-related conditions years after losing weight, according to a 10-year-long ...
Apr 27, 2026
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An epigenetic mechanism by which tumors manage to hide from the body's immune defenses has just been described by an international scientific team led by the University of Liège and the Dana-Farber Cancer Institute. These ...
May 13, 2026
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In 2024, Professor Sebastian Kobold's research group at LMU University Hospital had already shown that the metabolite prostaglandin E2 can block T cells—the killer cells of the immune system—in the vicinity of a tumor, such ...
Feb 16, 2026
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Researchers at the University of Liège have identified a key genetic regulator that enables macrophages to reach full maturity and preserve the health of our organs. The MafB factor, a veritable "molecular switch," activates ...
Feb 26, 2026
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A naturally occurring byproduct of liver metabolism—the ketone body, β-hydroxybutyrate (BHB)—can strengthen the fitness and antitumor activity of CAR T cells. The findings, reported on March 6, 2026 in the journal Cell, by ...
Mar 6, 2026
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