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Infectious diseases news

New RNA vaccine strategy aims to build broader immunity against mutating viruses

New research by Malaghan's Connor Laboratory, published in PNAS, shows how directing the immune system toward conserved areas of the COVID virus and its many variants using RNA technology could be a significant step toward ...

Three shifting immune states in sepsis could explain why treatments miss their window

Researchers have mapped how the immune response in people with sepsis changes over time. The work, led by King's College London, could help pave the way for treatments that target the specific parts of the immune system that ...

Early trials for 'common cold' vaccine offer encouraging signs

A vaccine designed to protect against rhinoviruses, which cause the great majority of common colds and exacerbate chronic respiratory illnesses, has shown encouraging early results in a phase 1 clinical trial. Initial findings ...

Egyptian group developing Ebola vaccine

An Egyptian pharmaceutical firm is developing a potential vaccine against the deadly Ebola strain raging in the Democratic Republic of Congo (DRC), it announced Thursday.

WHO declares Uganda Ebola-free

Uganda was declared officially Ebola-free by the World Health Organization on Thursday after 42 days without a new case.

New approach cuts sepsis diagnosis from days to hours

Sepsis, a life-threatening condition that stems from the body trying to fight off an infection, plagues more than 1.5 million patients a year in the U.S. alone, with one in three deaths recorded in hospitals attributed in ...

How pregnancy itself drives deadly hepatitis E outcomes

Researchers have uncovered a biological mechanism that helps explain why hepatitis E virus infections can be especially severe—and often fatal—during pregnancy, finding that normal pregnancy-related hormonal changes inadvertently ...

Wastewater may offer an early warning of pertussis outbreaks

Pertussis, or whooping cough, continues to cause periodic outbreaks worldwide and can be especially dangerous for infants who have not completed vaccination. Yet conventional surveillance depends on people seeking medical ...

Commonly used drugs show small benefit for long COVID fatigue

Over-the-counter antihistamines and a prescription anti-inflammatory drug both have a small benefit in reducing long COVID fatigue among people receiving care from specialist long COVID clinics, according to new findings ...

A rare, Ebola-like virus is spreading. Are we prepared?

A growing outbreak of the rare Bundibugyo virus in the Democratic Republic of Congo highlights the need for better planning against lesser-known but potentially deadly infectious diseases, according to a review article by ...

How immune cells in our gut mesentery fight salmonella

Widely recognized as the face of food poisoning, salmonella bacteria lurk in raw meat and poultry, on pets, and in unpasteurized dairy products. If untreated, extreme cases can lead to full-body infections, like typhoid fever. ...