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Inflammatory disorders news

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Inflammatory disorders

A faulty iron hormone in the skin may be the root cause of psoriasis

Scientists may have uncovered the root cause of psoriasis, a chronic and sometimes debilitating skin disease that affects 2–3% of the global population. The condition is characterized by red, scaly patches that impact the ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Inflammatory disorders

How the health of your gut microbiome can affect your skin

The skin is the largest organ of the human body. Not only does it act as the first line of defense against external stressors such as environmental toxins, pathogens and pollutants, our skin can also reveal much about our ...

Inflammatory disorders

Prophylaxis after relapse of ANCA-associated vasculitis

ANCA-associated vasculitis (AAV) is an autoimmune disease involving vascular inflammation and the formation of autoantibodies (anti-neutrophil cytoplasmic antibodies—ANCA). AAV diseases include a variety of conditions accompanied ...

Diseases, Conditions, Syndromes

Psoriasis patients' mental health is more than skin-deep

Treatment of the common disease psoriasis, usually focuses on treating the skin. However, psoriasis patients often have other physical diseases that can bring on depression, anxiety, and suicide. A new study from Umeå University, ...

Immunology

New effective treatment for inflammatory diseases found

New research conducted by the University of Liverpool and AKL Research and Development Ltd (AKLRD), published in Inflammopharmacology, highlights the potential benefits of a new drug treatment on the human body's immune response ...

Inflammatory disorders

1990 to 2017 saw increase in prevalence, incidence of psoriasis

(HealthDay)—From 1990 to 2017, there were increases in the global prevalence, incidence, and burden of suffering related to psoriasis, according to a report published in the May issue of the International Journal of Dermatology.

Immunology

Inflammation: part hero, part villain

For many years, inflammation was considered one of medicine's chief enemies. Experts viewed it as a side effect of illness and injury, a negative byproduct of the body's efforts to heal. One managed and banished it whenever ...

Alzheimer's disease & dementia

Psoriasis tied to higher Alzheimer disease risk

(HealthDay)—The incidence of Alzheimer disease (AD) is significantly higher in patients with psoriasis versus individuals without psoriasis, according to a Korean study published online April 15 in Scientific Reports.

Medical research

New approach to treating arthritis and other inflammatory diseases

Researchers from Peter Mac have discovered an innovative way to dampen severe inflammation in mice, uncovering a potential new therapeutic approach for inflammatory and autoimmune conditions such as arthritis, psoriasis and ...

Medical research

Worm extract found to reduce inflammation in mouse models

A team of researchers from Germany, Switzerland, Sweden and Australia has found that a substance isolated from roundworm larvae was able to reduce inflammation in the airways of mice. In their paper published in the journal ...

Inflammatory disorders

Bedroom air filters help asthmatic children breathe easier

Using a bedroom air filter that traps fine particles of pollution with diameters smaller than 2.5 micrometers can significantly improve breathing in asthmatic children, a new study by American and Chinese scientists shows.

Medical research

Gut enzyme IAP found to prevent aging and frailty in animal models

It's now accepted that gut-barrier dysfunction and gut-derived chronic inflammation play a role in human aging, but how that process is regulated is still largely a mystery. A team led by Richard Hodin, MD, chief of the Division ...