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Inflammatory disorders news

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Diseases, Conditions, Syndromes

Treatment for chronic rhinitis yields significant clinical improvements

Neurent Medical, a company developing non-surgical interventions to treat chronic inflammatory sinonasal diseases, has released positive six-month results from the PARAGON clinical study in Ear, Nose & Throat Journal.

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Dentistry

Altered blood markers detected in individuals with periodontitis

Individuals with periodontitis have altered concentrations of various proteins in their blood, according to a new study from Umeå University, Sweden. These findings pave the way for research into biomarkers for periodontitis ...

Immunology

How chronic inflammation may drive down dopamine and motivation

Growing evidence shows that the brain's dopamine system, which drives motivation, is directly affected by chronic, low-grade inflammation. A new paper proposes that this connection between dopamine, effort and the inflammatory ...

Diseases, Conditions, Syndromes

Adult-onset IBD linked to higher mortality

While the onset of inflammatory bowel disease (ulcerative colitis or Crohn's disease) in adulthood is tied to a higher mortality, the actual number of deaths has been falling, a Swedish study from Karolinska Institutet published ...

Inflammatory disorders

Combination therapy advisable for IBS

The more abnormalities in intestinal and brain function that IBS sufferers have, the more severe their symptoms of this functional bowel disorder, and the more adversely their everyday life is affected. This is shown by a ...

Diseases, Conditions, Syndromes

Researchers identify previously unknown bacterial strain

Clinicians at the Department of Neurology of MedUni Vienna/Vienna General Hospital identified muscle weakness and severe fatigue in a previously healthy patient, to the extent that he was soon confined to a wheelchair. These ...

Immunology

Polysulfide donors strongly suppress inflammatory responses

Researchers from Japan have developed a new polysulfide donor: a chemical compound composed of chains of sulfur atoms that can artificially increase reactive sulfur species (chemically reactive molecules containing sulfur) ...

Inflammatory disorders

New therapeutic strategy to prevent gastrointestinal disease

Food allergies, celiac disease, inflammatory bowel disease (IBD), diarrhea and other gastrointestinal diseases have something in common: all have been linked to epithelial barrier loss. The gut epithelial barrier—that critical ...

Arthritis & Rheumatism

A new treatment for gout lowers the urinary acid level in the body

Gout is an inflammatory disease that can cause very painful attacks. The illness is also called podagral, or colloquially "The Captain's syndrome". It primarily affects men, particularly over 40 years of age. Symptoms of ...

Inflammatory disorders

'Inflamm-aging' causes loss of bone healing ability in the elderly

Increases in chronic inflammation—not the passage of time—is the main reason why injured bones do not heal as well with age. This is the finding of a study in mice and humans published March 18 in the Proceedings of the ...

Immunology

Skin repair eliminates 'inflamm-aging' linked to chronic disease

Skin is the body's largest organ, and scientists at UC San Francisco and the San Francisco Veterans Administration (VA) Health Care System think it may be to blame for body-wide inflammation linked to numerous chronic diseases ...

Medical research

Avocado seed extract shows promise as anti-inflammatory compound

An extract from the seeds of avocados exhibited anti-inflammatory properties in a laboratory study, according to Penn State researchers, and it represents a potential source for novel anti-inflammatory compounds that could ...