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Inflammatory disorders news

Diseases, Conditions, Syndromes

Home-based phototherapy as effective as office-based for psoriasis

For plaque or guttate psoriasis, home-based narrowband ultraviolet B phototherapy is as effective as office-based phototherapy, according to a study published online Sept. 25 in JAMA Dermatology to coincide with the annual ...

Inflammatory disorders

Thaumatin, a natural sweetener with anti-inflammatory potential

A new study by the Leibniz Institute for Food Systems Biology at the Technical University of Munich shows for the first time that bitter tasting protein fragments (peptides) are produced in the stomach during the digestion ...

Immunology

Nanobodies help decode the central mechanism of inflammation

The formation of pores by a particular protein, gasdermin D, plays a key role in inflammatory reactions. During its activation, an inhibitory part is split off. More than 30 of the remaining protein fragments then combine ...

Medications

FDA approves Bimzelx for three new indications

The U.S. Food and Drug Administration has approved Bimzelx (bimekizumab-bkzx) for the treatment of adults with active psoriatic arthritis (PsA), adults with active nonradiographic axial spondyloarthritis (nr-axSpA) with objective ...

Diseases, Conditions, Syndromes

Houston pollen count has spiked dramatically over the last decade

New data from the Houston area reveals spiking levels of ragweed, elm and cedar elm pollen as well as mold spore counts as we enter the fall season. An allergy expert at Baylor College of Medicine breaks down this information ...

Inflammatory disorders

FDA approves Tremfya for ulcerative colitis

The U.S. Food and Drug Administration has approved Johnson & Johnson's Tremfya (guselkumab) for the treatment of adults with moderately to severely active ulcerative colitis.

Inflammatory disorders

Diagnostic tool identifies puzzling inflammatory diseases in kids

RNA performs a number of biological duties, from delivering genetic information to manufacturing proteins. But RNA is also expelled from cells via cell death or active release, and can then find its way into blood plasma.

Inflammatory disorders

Potential new therapy for Crohn's, colitis identified

People with inflammatory bowel disease (IBD) live with frequent, miserable episodes of abdominal pain, diarrhea and in severe cases, rectal bleeding. Standard treatments are aimed at directly suppressing inflammation, but ...

Immunology

Molecular clock influences immune cell responses

Scientists have recently recognized that cells of the same type can behave differently in response to stimulation. In a new study, Yale researchers have shown how these varied responses are due in part to a desynchronized ...

Neuroscience

Inflammation signals induce dormancy in aging brain stem cells

In old age, the amount of stem cells in the brains of mice decreases drastically. The remaining ones protect themselves from completely vanishing by entering a state of dormancy, scientists from the German Cancer Research ...

Immunology

Stopping inflammation from becoming chronic

An international research team led by Friedrich Schiller University in Jena has developed a highly sensitive cell model to study the complex effects – and side effects – of anti-inflammatory drugs, with the ultimate aim ...

Immunology

Patients' own cells could be the key to treating Crohn's disease

A new technique using patients' own modified cells to treat Crohn's disease has been proven to be effective in experiments using human cells, with a clinical trial of the treatment expected to start in the next six months.

Immunology

Venoms are sources in the search for new medicines

Animal venoms are the subject of study at the Butantan Institute in São Paulo. But in this case, the idea is not to find antidotes, but rather to use the properties of the venoms themselves to identify molecular targets ...

Diseases, Conditions, Syndromes

New guidelines outline new treatment management for psoriasis

Two new guidelines about the treatment and management of psoriasis have been released by the American Academy of Dermatology, providing physicians with new evidence-based standards of how to treat the disease through the ...

Immunology

Regulating the MS-causing properties of Th17 cells

An international study group led by researchers from Osaka University identifies a protein regulator responsible for inducing the pathogenic properties of Th17 cells, leading to multiple sclerosis and other inflammatory autoimmune ...

Inflammatory disorders

Diagnostic delays common in inflammatory bowel disease

(HealthDay)—Diagnostic delays are common in inflammatory bowel disease, with 68 percent of patients reporting a delay in diagnosis, according to a study presented at the 2019 Crohn's & Colitis Congress, held from Feb. 7 ...