National University of Singapore researchers developed an approach to target highly resistant triple-negative breast cancers (TNBCs) by interfering with their energy production using cytotoxic gold-metformin prodrugs.
Apr 22, 2021
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Cases of chronic inflammatory bowel disease (IBD), such as Crohn's disease and ulcerative colitis, are on the rise worldwide. The benefits of current medications to treat patients with these diseases are limited by problematic ...
Jul 17, 2023
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To give cancer treatments the greatest possible chance of success, patients are often treated with multiple drugs that attack the cancer using different mechanisms. A team of researchers has now combined three highly potent ...
Sep 19, 2023
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The analysis of all small molecules in an organism (the metabolome) has huge potential for medical diagnostics. A German research team is investigating this with nuclear magnetic resonance spectrometry (NMR).
Jul 24, 2023
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Photothermal therapy (PTT) is a safe cancer hyperthermia strategy that utilizes photothermal conversion agents to convert light energy into heat to ablate cancer cells.
Aug 1, 2022
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Alzheimer's disease is the most common neurodegenerative disorder in which neurons gradually die off, leading to dementia. The exact mechanism and causes of this disorder have not yet been identified. However, it is known ...
May 26, 2021
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Extensive blood loss after injuries is life-threatening and must be counteracted as fast as possible. Relatively small volume injections of solutions of a novel star-shaped polymer could compensate for the loss of fluid without ...
Jul 3, 2024
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Immunotherapies for cancer aim to induce the immune system to combat cancer cells more effectively. In the journal Angewandte Chemie International Edition, a Chinese research team has now described a new, modular strategy ...
Aug 23, 2023
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