A University of Virginia School of Medicine researcher is developing a two-fisted, antibody-based approach to destroy deadly ovarian cancer—an approach he believes could also be modified to kill breast, prostate and other ...
Aug 30, 2018
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8
St. Jude Children's Research Hospital investigators have completed the most comprehensive analysis yet of a common pediatric solid tumor, identifying weaknesses to target and a promising precision medicine that is now in ...
Aug 23, 2018
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When scientists at ETH Zurich analysed very large amounts of genetic cancer data, they found previously unresearched molecular changes. These could help in developing new personalised cancer treatments.
Aug 6, 2018
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In more than half of all prostate tumors, two genes—one for a transcription factor called ERG, the other a testosterone-triggered gene called TMPRSS2—become fused together, resulting in excess ERG expression. The TMPRSS2-ERG ...
Aug 3, 2018
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A Massachusetts General Hospital (MGH) research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma—the second most common bone cancer in children and young adults—unleashes ...
Aug 2, 2018
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Despite being studied for decades, the chemotherapy drug cisplatin is revealing new aspects of how it works. Researchers at Winship Cancer Institute of Emory University have identified an enzyme responsible for making tumors ...
Jul 19, 2018
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A Ludwig Cancer Research study explains why a particular mutation in the epidermal growth factor receptor (EGFR), a cell surface protein, results in more aggressive tumors and poorer overall survival of patients diagnosed ...
Jul 9, 2018
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UC San Francisco researchers have identified the sequence of genetic changes that transform benign moles into malignant melanoma in a large cohort of human skin cancer patients and have used CRISPR gene editing to recreate ...
Jul 9, 2018
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A poorly understood mutation in the brain cancer glioblastoma (GBM) is now being implicated for the first time as the driver of rare but deadlier cases of the disease, a team of researchers from the Perelman School of Medicine ...
Jul 9, 2018
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Most cells in the human body have a cilium, a slender cell protuberance that picks up signals from the cell's external environment. Researchers at the University of Zurich have now shown that these fine sensory antennae play ...
Jul 2, 2018
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