Researchers from UCLA and Long Beach Memorial Medical Center have found that two targeted therapies could be more effective if used in combination to treat squamous cell carcinomas of the lung. The two drugs, MLN128 and CB-839, ...
Apr 12, 2018
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Melanoma, a relatively rare but deadly skin cancer, has been shown to switch differentiation states—that is, to regress to an earlier stage of development—which can lead it to become resistant to treatment. Now, UCLA ...
Apr 12, 2018
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The canine transmissible venereal tumor is a contagious cancer that has spread by mating among dogs worldwide. One unique feature of this cancer is that, for unclear reasons, it regresses spontaneously or a few weeks after ...
Apr 9, 2018
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A promising class of drugs known as CD40 monoclonal antibodies could be the spark needed to light the fire in the immune system of patients who don't respond to the newer cancer immunotherapies.
Apr 9, 2018
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Obesity is the second-leading preventable cause of cancer and represents one of the greatest threats to global human health. But it has not been clear exactly how whole-body metabolism affects tumor formation. In particular, ...
Apr 9, 2018
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Researchers from The University of Texas MD Anderson Cancer Center have found a startling amount of new information about molecular features of tumors as well as identified previously unknown cancer subtypes based on a comprehensive ...
Apr 5, 2018
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Typically cancers are classified by where they originate in the body—think breast cancer, stomach cancer, and so on. But a collaboration called the Pan-Cancer Initiative, launched in 2012 at a meeting in Santa Cruz, California, ...
Apr 5, 2018
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Two new biomarkers for a type of cancer in children called neuroblastoma have been identified in a study published in the journal Cancer Cell. The findings are expected to have immediate significance for disease prognosis, ...
Mar 13, 2018
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Can genes normally expressed only in the eye be activated in brain tumours? The phenomenon, though surprising, has been observed in certain types of medulloblastoma, paediatric tumours of the cerebellum. Researchers from ...
Mar 12, 2018
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Some scientists have hypothesized that tumor-promoting changes in cells during cancer development—particularly an epigenetic change involving DNA methylation—arise from rogue cells escaping a natural cell deterioration ...
Feb 22, 2018
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