An international research team has succeeded in stopping the growth of malignant melanoma by reactivating a protective mechanism that prevents tumor cells from dividing. The team used chemical agents to block the enzymes ...
Feb 22, 2018
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273
A study by researchers at Dana-Farber Cancer Institute has illuminated a specific mechanism by which estrogen receptor-positive (ER+) breast cancers can become resistant to standard therapies and metastasize.
Feb 12, 2018
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15
Genomic profiling of mostly untreatable and deadly nerve sheath tumors led scientists to test a possible therapeutic strategy that inhibited tumor growth in lab tests on human tumor cells and mouse models, according to research ...
Feb 12, 2018
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125
What happens when the most common and least threatening type of cancer gets complicated?
Feb 1, 2018
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41
New drugs that activate the immune system to target cancer cells have improved the lives of many patients with cancer. However, immunotherapies are not effective in all patients, and the success of these therapies depends ...
Jan 30, 2018
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5
Screening a class of recently-developed drug compounds—so-called "CDK inhibitors" capable of blocking CDK7/12/13 proteins—against hundreds of different human cancer cell lines, researchers at Dana-Farber/Boston Children's ...
Jan 25, 2018
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377
A study published in Cancer Cell by researchers of the Molecular Oncology Program at the Spanish National Cancer Research Centre (CNIO) shows that the elimination of the c-Raf kinase by genetic manipulation causes the regression ...
Jan 25, 2018
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8
A new study shows that stress accelerates the development of pancreatic cancer by triggering the release of "fight-or-flight" hormones. Beta-blockers—commonly used medications that inhibit these hormones—were found to ...
Jan 10, 2018
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16
St. Jude Children's Research Hospital oncologists have discovered the cell type that gives rise to rhabdomyosarcoma, the most prevalent soft tissue cancer in children. Previously, scientists thought the cancer arose from ...
Jan 8, 2018
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352
Cancer researchers today announced they have developed a way of sidelining one of the most dangerous "bad actors" in leukemia. Their approach depends on throwing a molecular wrench into the gears of an important machine that ...
Jan 8, 2018
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