Developmental Cell

Medical research

Metabolic remodeling during regeneration

A healthy liver has a significant capacity to regenerate after injury or disease, but little was known about the accompanying detailed changes in cell metabolism. An international research team, that includes scientists from ...

Cancer

Origin of cancer wasting identified in fruit flies

The progressive wasting of muscle and fat tissue throughout the body is one of the most visible and heartbreaking manifestations of cancer, yet little is known about how tumors cause distant tissues to degenerate. Two independent ...

Cardiology

Finding suggests ways to promote adult heart tissue regeneration

Injured hearts do not heal themselves. Heart muscle cells, or cardiomyocytes, do not proliferate as much as necessary to replace dead tissue with new, pumping cells. Consequently, most people who had a severe heart attack ...

Medical research

Researchers discover drug cocktail that increases lifespan

A team of researchers led by Principal Investigator Dr. Jan Gruber from Yale-NUS College has discovered a combination of pharmaceutical drugs that not only increases healthy lifespan in the microscopic worm Caenorhabditis ...

Cancer

Study shows how an opportunistic microbe kills cancer cells

New study results show for the first time how dying cells ensure that they will be replaced, and suggests an ingenious, related new approach to shrinking cancerous tumors. A research team from Rush University Medical Center ...

Neuroscience

Giant proteins determine properties of neurons

Giant membrane-associated proteins called ankyrins extend into the cytoplasm to arrange and stabilize microtubules in axons and synapses. This determines not only the diameter and hence the functional properties of axons, ...

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