Developmental Cell

Neuroscience

Giant proteins determine properties of neurons

Giant membrane-associated proteins called ankyrins extend into the cytoplasm to arrange and stabilize microtubules in axons and synapses. This determines not only the diameter and hence the functional properties of axons, ...

Medical research

Metabolic remodeling during regeneration

A healthy liver has a significant capacity to regenerate after injury or disease, but little was known about the accompanying detailed changes in cell metabolism. An international research team, that includes scientists from ...

Cancer

Golgi trafficking controlled by G proteins

A family of proteins called G proteins are a recognized component of the communication system the human body uses to sense hormones and other chemicals in the bloodstream and to send messages to cells. In work that further ...

Cardiology

Finding suggests ways to promote adult heart tissue regeneration

Injured hearts do not heal themselves. Heart muscle cells, or cardiomyocytes, do not proliferate as much as necessary to replace dead tissue with new, pumping cells. Consequently, most people who had a severe heart attack ...

Cancer

Team identifies oncogene regulated by nutrients

Scientists from the Growth Factors, Nutrients and Cancer Group at the Spanish National Cancer Research Center (CNIO), led by Nabil Djouder, have discovered that the MCRS1 protein, in response to an excess of nutrients, induces ...

Neuroscience

Scientists uncover new details in how sense of smell develops

Dogs, known for their extraordinarily keen senses of smell, can be trained to use their sensitive sniffers to find drugs, bombs, bed bugs, missing hikers and even cancer. Among dogs and other animals that rely on smell, at ...

Diabetes

Research shows nerve growth protein controls blood sugar

Research led by a Johns Hopkins University biologist demonstrates the workings of a biochemical pathway that helps control glucose in the bloodstream, a development that could potentially lead to treatments for diabetes.

Cardiology

Tension makes the heart grow stronger

By taking videos of a tiny beating zebrafish heart as it reconstructs its covering in a petri dish, scientists have captured unexpected dynamics of cells involved in tissue regeneration. They found that the depleted heart ...

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