Journal of Clinical Investigation

Medical research

Study pinpoints molecular targets of transplant rejection

Researchers from the University of Sydney and Monash University have made a significant discovery that uncovers what is happening at the molecular level when an organ transplant is recognized as foreign by the immune system.

HIV & AIDS

Treatment strategy may lead to HIV cure

Armed with a novel strategy they developed for bolstering the body's immune response, scientists at Albert Einstein College of Medicine have successfully suppressed HIV infections in mice—offering a path to a functional ...

Diseases, Conditions, Syndromes

One coronavirus vaccine may protect against other coronaviruses

Northwestern Medicine scientists have shown for the first time that coronavirus vaccines and prior coronavirus infections can provide broad immunity against other, similar coronaviruses. The findings build a rationale for ...

Neuroscience

Altering metabolism in immune cells helps damaged nerves recover

Peripheral nerves—the nerves outside the brain and spinal cord—have the capacity for regeneration, but the rate of renewal is so slow that many nerve injuries lead to incomplete recovery and permanent disability for patients. ...

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