Journal of Experimental Medicine

Diseases, Conditions, Syndromes

Editing mosquito's gene wards off malaria and halts reproduction

Scientists have looked for immune system factors that might help mosquitoes ward off pathogens such as malarial parasites and indirectly protect humans from infection. Yale researchers found one by editing a single gene, ...

Genetics

Scientists find molecular key to body making healthy T cells

In a finding that could help lead to new therapies for immune diseases like multiple sclerosis and IBD, scientists report in the Journal of Experimental Medicine identifying a gene and family of proteins critical to the formation ...

Immunology

Creatine powers T cells' fight against cancer

Creatine, the organic acid that is popularly taken as a supplement by athletes and bodybuilders, serves as a molecular battery for immune cells by storing and distributing energy to power their fight against cancer, according ...

Oncology & Cancer

Drug shows promise as immune therapy for cancer

A therapy developed by Yale researchers stimulates immune cells to shrink or kill tumors in mice, according to a new study published in the Journal of Experimental Medicine. The therapy is effective alone or in combination ...

Alzheimer's disease & dementia

Targeting immune cells may be potential therapy for Alzheimer's

Messy tangles of a protein called tau can be found in the brains of people with Alzheimer's disease and some other neurodegenerative diseases. In Alzheimer's, the tangles coalesce just before tissue damage becomes visible ...

Diseases, Conditions, Syndromes

Researchers identify new therapeutic target for pulmonary fibrosis

Researchers in Japan have identified a genetic mutation that causes a severe lung disease called idiopathic pulmonary fibrosis (IPF) by killing the cells lining the lung's airways. The study, which will be published October ...

Oncology & Cancer

Researchers discover a new form of immunotherapy

A new form of immunotherapy that has so far been tested on mice makes it probable that oncologists in the future may be able to treat some of the patients who are not responding to existing types of immunotherapy. Instead ...

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