Journal of Experimental Medicine

Medical research

Cell 'canibalism' educates our defenses

Phagocytosis is a biological mechanism whereby specialized cells ingest and degrade old, dead, or damaged cells to prevent tissue damage due to their accumulation. But phagocytosis appears to also have an educational role. ...

Medical research

Sperm study reveals testes repair cells

Scientists have discovered a tiny group of cells that is critical to repairing damage to the testes. Blocking the cells prevents repair to tissue involved in producing healthy sperm, the research has found. The findings shed ...

Inflammatory disorders

Researchers find molecular trigger for brain inflammation

Brain inflammation is a key component of multiple sclerosis, Alzheimer's, Parkinson's, ALS, and most other major neurodegenerative diseases. How inflammation starts, how it's sustained, and how it contributes to these diseases ...

Genetics

Genetic control of immune cell proliferation

Germinal centers are transient structures in the lymph nodes where antibody-producing B cells proliferate and differentiate at extraordinary rates. Germinal centers can be visually divided into a dark zone and light zone. ...

Diseases, Conditions, Syndromes

Anthrax spores use RNA coat to mislead immune system

Researchers from Harvard Medical School have discovered that the body's immune system initially detects the presence of anthrax spores by recognizing RNA molecules that coat the spores' surface. But this prompts an unfavorable ...

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