Journal of Experimental Medicine

Diseases, Conditions, Syndromes

Hepatitis B: Natural controllers shed light on immunity mechanisms

Infections in humans caused by the hepatitis B virus (HBV) represent a major public health problem. Despite the availability of effective protective vaccines, more than 250 million individuals worldwide are chronically infected ...

Diseases, Conditions, Syndromes

Researchers develop new mouse model for SARS-CoV-2

Researchers at Yale University School of Medicine have developed a new mouse model to study SARS-CoV-2 infection and disease and to accelerate testing of novel treatments and vaccines against the novel coronavirus. The study, ...

Oncology & Cancer

How breast cancer cells sneak past local immune defenses

Cold Spring Harbor Laboratory (CSHL) Associate Professor Mikala Egeblad and her colleagues describe a newly understood way by which breast cancer cells sabotage a key player in the body's immune system. That key player provides ...

Immunology

B cells and their function in the immune system

Whenever a germ gets into the human body, the immune system usually responds immediately to fight off the enemy attacker. One of our defense system's most important strategies involves B lymphocytes, also known as B cells, ...

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