An LMU team has identified an enzyme that is essential for DNA repair. Loss of this factor leads to cell death when cancer cells accumulate DNA damage. Chemical inhibition of the target protein offers a possible strategy ...
Dec 4, 2020
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Utah scientists have discovered new functions of a key cellular machine that regulates gene packaging and is mutated in 20% of human cancers. The study was published in print today in the journal Molecular Cell.
Nov 19, 2020
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One of the novel coronavirus' most insidious tricks is that it can block the ability of cells to produce protective proteins without hindering its own ability to replicate.
Nov 5, 2020
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Martin Enge's research group at the department of Oncology-Pathology has developed a new method for joint analysis of a cell's state and accumulated genetic variation in single cells, applied to childhood leukemias and other ...
Oct 21, 2020
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A specific region of messenger RNAs, the 3' untranslated region (3'UTR), plays an important role for cells to function properly. During embryonic development, 3'UTRs in hundreds of RNAs lengthen exclusively in neurons, which ...
Oct 19, 2020
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Findings by Monash Biomedicine Discovery Institute (BDI) researchers have pointed to a new combination of treatments that may help breast cancer patients with certain gene mutations.
Oct 15, 2020
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Patients with BRCA1/2 mutations are at higher risk for breast, ovarian and prostate cancers that can be aggressive when they develop—and, in many cases, resistant to lifesaving drugs. Now scientists at The University of ...
Sep 22, 2020
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A team including Wei Liu, assistant professor in ASU's School of Molecular Sciences (SMS) and the Biodesign Institute's Center for Applied Structural Discovery, has published a paper today in Molecular Cell that offers promising ...
Aug 19, 2020
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The androgen receptor is the primary driver of the initiation and growth of prostate cancer, the second-leading cause of death in men. Looking to have a better understanding of how the androgen receptor works in cancer, researchers ...
Jul 14, 2020
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An experimental cancer drug can extend the life of mice with Rett Syndrome, a devastating genetic disorder that afflicts about one of every 10,000 to 15,000 girls within 6 to 18 months after birth, Yale researchers report ...
Jun 10, 2020
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