Researchers in the Muir Lab at Princeton University's Department of Chemistry have completed the first comprehensive analysis of cancer-associated histone mutations in the human genome, featuring both biochemical and cellular ...
Mar 1, 2021
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39
A collaboration led by Scripps Research has developed a way to separate the beneficial anti-inflammatory properties of a group of steroids called glucocorticoids from some of their unwanted side-effects, through an optimization ...
Feb 2, 2021
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95
Quitting smoking tops many New Year's resolution lists, but a nicotine addiction is hard to curb.
Jan 12, 2021
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100
Multiple myeloma is a cancer of the white blood cells, and patients diagnosed with this disease commonly die within five years. Clinicians often treat multiple myeloma with the drug thalidomide and structurally similar drugs ...
Sep 21, 2020
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65
A promising molecular pair has offered hope that could lead to the development of a new treatment to slow down Parkinson's disease, a study by Nanyang Technological University, Singapore (NTU Singapore) and Harvard University ...
May 27, 2020
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198
The endogenous compound anandamide—often referred to as the body's own marijuana—plays a role in erasing memories of a traumatic event. This was discovered by an international team led by Leiden chemist Mario van der ...
May 12, 2020
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1256
The commonly used chemotherapy drug doxorubicin can damage heart muscle, in some cases leading to severe or lethal heart failure. A new study led by Albert Einstein College of Medicine researchers and involving zebrafish ...
Mar 4, 2020
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108
Two recently approved leukemia drugs could be enlisted against treatment-resistant lung cancer, with a clinical trial expected to launch in Toronto and Zagreb, Croatia, later this year to evaluate one of them.
Feb 24, 2020
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122
In the natural course of events, multicellular organisms frequently need to eliminate cells. In humans, for example, superfluous tails, finger webbing, immune cells raised with wrongthink or neurons making inappropriate friends ...
The cells of most patients' cancers are resistant to a class of drugs, called proteasome inhibitors, that should kill them. When studied in the lab, these drugs are highly effective, yet hundreds of clinical trials testing ...
May 28, 2019
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