New discoveries about a built-in rapid reaction system that triggers inflammatory responses when people are exposed to allergens, such as insects, mites and fungi, also may hold the keys to helping more people manage their ...
Sep 16, 2021
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Regulatory T cells (TReg) are essential to regulating the immune system. However, there are several different types of TReg cells, and scientists are only now beginning to differentiate among them and understand their functions ...
Sep 7, 2021
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178
When pathogens invade the human body, a rapid response is required. At the forefront of the immune response are special immune cells. They reside in various tissues such as the lungs, liver, skin and intestines, where they ...
Aug 30, 2021
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586
In a significant step forward in understanding the crucial role tissue-resident memory T (TRM) cells play in the immune system, researchers have for the first time described how the cells behave in different tissues around ...
Aug 24, 2021
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Just as it is for marathoners who've completed a 26-mile run, or shrubs that have gone without water in a heatwave—exhaustion is an unavoidable fact of life. Dogs get exhausted after herding sheep; birds turn in for the ...
Yale researchers have discovered the underlying genetic cause of a rare childhood disorder that mimics inflammatory bowel disease, a finding that may help researchers uncover the roots of a host of other inflammatory and ...
Jul 29, 2021
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436
Chronic viral infections and cancer can cause "killer" T cells in the immune system to take on a state of dysfunction or exhaustion whereby they can no longer react to infectious invaders or abnormal cells like normal "memory" ...
Jul 28, 2021
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552
Researchers in the Perelman School of Medicine at the University of Pennsylvania have illuminated an important limitation of the immune system in prolonged battles against cancers or viruses: T cells, which are among the ...
Jul 26, 2021
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406
Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion.
Jul 19, 2021
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Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers. ...
Jul 16, 2021
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