Researchers in the Perelman School of Medicine at the University of Pennsylvania have illuminated an important limitation of the immune system in prolonged battles against cancers or viruses: T cells, which are among the ...
Jul 26, 2021
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Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion.
Jul 19, 2021
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Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers. ...
Jul 16, 2021
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Adenovirus vaccine vectors, such as the ChAdOx1 nCov-19 construct which has risen to prominence as a major vaccine for COVID-19, may generate robust long-term immune system responses, according to scientists from the Universities ...
Jul 15, 2021
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New research led by scientists at La Jolla Institute for Immunology (LJI) and the University of Liverpool may explain why many cancer patients do not respond to anti-PD-1 cancer immunotherapies—also called checkpoint inhibitors.
Jun 24, 2021
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Researchers investigating a group of microscopic cells have discovered they can put the brakes on the rapid development of melanoma lesions.
Jun 8, 2021
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Nearly a quarter of the world's population is estimated to be infected with Mycobacterium tuberculosis (M.tb), the pathogen that causes tuberculosis, but less than 15 percent of infected individuals develop the disease.
Jun 4, 2021
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The immune system's B cells have the unique distinction of being the only cells in the human body that evolve, in real time—and an international team of scientists announced in Nature Immunology that they have uncovered ...
May 25, 2021
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A Ludwig Cancer Research study has discovered how to revive a powerful but functionally inert subset of anti-cancer immune cells that are often found within tumors for cancer therapy.
May 24, 2021
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Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I. Upregulating expression of this protein could strengthen the immune ...
May 21, 2021
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