Primary immunodeficiencies, such as severe combined immunodeficiency disease (SCID), occur when the immune system does not work properly, leading to increased susceptibility to various infections, autoimmunity, and cancers. ...
Jul 16, 2021
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Adenovirus vaccine vectors, such as the ChAdOx1 nCov-19 construct which has risen to prominence as a major vaccine for COVID-19, may generate robust long-term immune system responses, according to scientists from the Universities ...
Jul 15, 2021
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New research led by scientists at La Jolla Institute for Immunology (LJI) and the University of Liverpool may explain why many cancer patients do not respond to anti-PD-1 cancer immunotherapies—also called checkpoint inhibitors.
Jun 24, 2021
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Researchers investigating a group of microscopic cells have discovered they can put the brakes on the rapid development of melanoma lesions.
Jun 8, 2021
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Nearly a quarter of the world's population is estimated to be infected with Mycobacterium tuberculosis (M.tb), the pathogen that causes tuberculosis, but less than 15 percent of infected individuals develop the disease.
Jun 4, 2021
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The immune system's B cells have the unique distinction of being the only cells in the human body that evolve, in real time—and an international team of scientists announced in Nature Immunology that they have uncovered ...
May 25, 2021
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A Ludwig Cancer Research study has discovered how to revive a powerful but functionally inert subset of anti-cancer immune cells that are often found within tumors for cancer therapy.
May 24, 2021
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173
Scientists from Hokkaido University have discovered a novel defensive response to SARS-CoV-2 that involves the viral pattern recognition receptor RIG-I. Upregulating expression of this protein could strengthen the immune ...
May 21, 2021
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63
One of the characteristic hallmarks of Alzheimer's disease (AD) is the buildup of amyloid-beta plaques in the brain. Most therapies designed to treat AD target these plaques, but they've largely failed in clinical trials. ...
Apr 15, 2021
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230
A team led by scientists at the UNC School of Medicine discovered an important vulnerability of the AIDS-causing retrovirus HIV, and has shown in preclinical experiments that a widely used diabetes drug, metformin, seems ...
Mar 29, 2021
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