Nature Methods

Neuroscience

iTango: New technique studies neuromodulation in real time

When we think of neuronal communication, we often picture a single neuron releasing molecular neurotransmitters into a junction called a synapse where they stimulate another neuron. But sometimes, instead of crossing a synapse, ...

Neuroscience

Tiny spheres of human cells mimic the brain, researchers say

The human brain is a highly organized, three-dimensional mass of cells responsible for our every move, thought and emotion. Snugly housed in the bony confines of the skull, it's also relatively inaccessible, making it difficult ...

Medical research

Observing the freely behaving brain in action

Scientists working at Caesar have developed a small head-mounted microscope that allows access to the inner workings of the brain. The new system enables measurement of activity from neuronal populations located in the deep ...

Medical research

Deep sea light shines on drug delivery potential

A naturally occurring bioluminescent protein found in deep sea shrimp—which helps the crustacean spit a glowing cloud at predators—has been touted as a game-changer in terms of monitoring the way drugs interact with live ...

Genetics

New method for genetic analysis of resting human immune cells

CD4+ T cells are important parts of the immune system and play a key role in defending the body against pathogens. As they possess a great variety of defense mechanisms against HIV in their resting state, they are infected ...

Medical research

Modeling COPD and asthma in a human small airway-on-a-chip

A research team at the Wyss Institute for Biologically Inspired Engineering at Harvard University leveraged its organ-on-a-chip technology to develop a model of the human small airway in which lung inflammatory diseases, ...

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