Proceedings of the National Academy of Sciences

Oncology & Cancer

Scientists show reprogrammed fat cells support tumor growth

Mutations of the tumor suppressor p53 not only have a growth-promoting effect on the cancer cells themselves, but also influence the cells in the tumor's microenvironment. Scientists at the German Cancer Research Center (DKFZ) ...

Oncology & Cancer

Researchers uncover on/off switch for breast cancer metastasis

Despite their promise, immunotherapies fail to treat many cancers, including over 80% of some of the most advanced breast cancers. And many of those patients who do respond still experience metastases eventually. New research ...

Psychology & Psychiatry

Multiple periods of loneliness may add up to higher mortality risk

Working from well-established research on the detrimental health effects of loneliness, University of Michigan researchers set out to study whether feeling lonely multiple times through the years leads to more serious illness ...

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