MeSH tree: D12.644.276.374.465.512
Chronic wounds remain a significant clinical challenge, in part because it is difficult to deliver sustained, localized immune signals that coordinate tissue repair. While cytokines play a central role in regulating inflammation ...
May 27, 2026
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Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have developed a new cytokine-armored CAR-T cell therapy that helps the immune system better attack aggressive brain tumors in mice while reducing dangerous ...
May 20, 2026
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Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from ...
Jan 31, 2026
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Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the ...
Jan 22, 2026
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Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and ...
Dec 4, 2025
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Glioblastoma is an aggressive brain cancer that almost always recurs after surgery and radiochemotherapy. Now, researchers have developed a biodegradable implant that can be placed directly into the brain cavity after tumor ...
Oct 29, 2025
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An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding interleukin 12 strategy that lets CAR-T cells treat prostate cancer in mice while curbing previously ...
Chimeric antigen receptor (CAR) T cell therapy, which uses a patient's own immune cells to fight cancer, has emerged as a powerful way to treat lymphoma and other blood cancers. But researchers have struggled to adapt the ...
Oct 1, 2025
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In the quest to design vaccines that better help the body's immune system fight disease, scientists are always looking for more tools for their arsenal.
Jun 6, 2025
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Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a dendritic-cell–natural-killer-cell circuit that suppresses leptomeningeal metastases in mouse models.
