MeSH tree: D12.644.276.374.465.512
Scientists at The Wistar Institute have identified a previously overlooked mediator in the body's response to life-threatening infections: hippuric acid, a metabolite produced when gut bacteria break down polyphenols from ...
Jan 31, 2026
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Scientists at the Icahn School of Medicine at Mount Sinai have developed an experimental immunotherapy that takes an unconventional approach to metastatic cancer: instead of going after cancer cells directly, it targets the ...
Jan 22, 2026
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Researchers at Mass General Brigham have modified a herpes simplex virus (HSV-1) that stimulates the immune system to attack glioblastoma cells. A single dose of the modified virus increased T-cell, natural killer cell, and ...
Dec 4, 2025
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Glioblastoma is an aggressive brain cancer that almost always recurs after surgery and radiochemotherapy. Now, researchers have developed a biodegradable implant that can be placed directly into the brain cavity after tumor ...
Oct 29, 2025
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An international collaboration of researchers, including Imperial College London and UCLA, has developed a collagen-binding interleukin 12 strategy that lets CAR-T cells treat prostate cancer in mice while curbing previously ...
Chimeric antigen receptor (CAR) T cell therapy, which uses a patient's own immune cells to fight cancer, has emerged as a powerful way to treat lymphoma and other blood cancers. But researchers have struggled to adapt the ...
Oct 1, 2025
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In the quest to design vaccines that better help the body's immune system fight disease, scientists are always looking for more tools for their arsenal.
Jun 6, 2025
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Memorial Sloan Kettering Cancer Center investigators report that T cell interferon-γ (IFNγ) orchestrates a dendritic-cell–natural-killer-cell circuit that suppresses leptomeningeal metastases in mouse models.
Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear away cellular debris—including the plaques typical of Alzheimer's disease. However, as our brains ...
Mar 17, 2025
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Researchers from Queen Mary University of London, the Chinese Academy of Sciences and Capital Medical University in Beijing have tested a virus treatment in eight patients with glioblastoma. The treatment was safe and effective ...
Nov 8, 2024
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