MeSH tree: D12.776.543.750.720
One of the things that makes brains so incredibly difficult to understand is their ability to adjust and adapt. Our learning experiences can set off complex signaling cascades that reshape neurons—and their synaptic connections—at ...
Sep 19, 2024
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One of the brain's most celebrated qualities is its adaptability. Changes to neural circuits, whose connections are continually adjusted as we experience and interact with the world, are key to how we learn. But to keep knowledge ...
Sep 16, 2024
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A team of brain and mental health specialists in China and the U.S. has uncovered some of the mechanics behind ketamine's rapid antidepressant effects. In their study, published in the journal Science, the group administered ...
A large, multi-institutional team of medical researchers reports that giving anorexic mice the peptide ACBP stimulated eating. In their paper published in the journal Science Translational Medicine, the group describes their ...
A research team—co-led by Penn Nursing—has made a significant breakthrough in understanding the complex neural circuitry underlying reward and addiction by identifying 34 distinct subtypes of medium spiny neurons (MSNs) in ...
Aug 14, 2024
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The connections between the nervous system and muscles develop differently across the kingdom of life. It takes newborn humans roughly a year to develop the proper muscular systems that support the ability to walk, while ...
Jul 31, 2024
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In humans and other animals, signals from a central circadian clock in the brain generate the seasonal and daily rhythms of life. They help the body to prepare for expected changes in the environment and also optimize when ...
Jul 24, 2024
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Opioids have long been known as natural substances with substantial pharmacological effects and have been used as effective painkillers. A very prominent example is morphine, which was first isolated and synthesized in the ...
Jul 17, 2024
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As opioid overdose deaths in the U.S. rose dramatically from 2014 to today, both Philadelphia, Pennsylvania, and Camden, New Jersey, cemented reputations as hotspots of the crisis.
Jul 17, 2024
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Researchers at the University of Arizona Health Sciences identified a new way to make opioids safer, increasing the pain-relieving properties of opioids while decreasing unwanted side effects through the spinal inhibition ...
Jul 16, 2024
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