How psychedelics push your brain to dream while awake: New study
A new study in mice suggests psychedelics make the brain more likely to "see" images from memory rather than what's actually in front of it.
Mar 14, 2026
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Amino Acids, Peptides, and Proteins: News and Research on Receptors, Neurotransmitter
MeSH tree: D12.776.543.750.720
Creating less trippy, more therapeutic 'magic mushrooms'
Psilocybin—the psychoactive compound in "magic mushrooms"—is gaining scientific attention for its potential in treating neuropsychiatric conditions including depression, anxiety, substance use disorders and certain neurodegenerative ...
Mar 6, 2026
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Ketamine reduces anxiety and social withdrawal in stressed adolescent mice
Ketamine is a powerful anesthetic used for surgery and acute pain management. But in recent years, it has also gained a reputation as a potential treatment for certain mental health conditions like stress and anxiety. In ...
How psychedelic drugs affect the brain: Animal study links hallucinations to memory fragments
Psychedelic substances are increasingly being used under medical supervision to treat anxiety disorders and depression. However, the mechanisms by which these substances influence our perception and consciousness are largely ...
Feb 13, 2026
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Both reward and aversion learning require the brain molecule sulfatase 1
Researchers at University of Tsukuba and their collaborators have demonstrated that learning from both rewarding and aversive outcomes requires a common brain molecule, sulfatase 1 (Sulf1). This extracellular enzyme removes ...
Jan 28, 2026
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A shared process underlies oral cancer pain and opioid tolerance
Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and makes opioids less effective. The findings point to a shared mechanism underlying both oral cancer pain ...
Jan 27, 2026
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Alpha-2 receptor drugs reduce heavy alcohol drinking, study finds
Alcohol use is widespread and alcohol use disorder (AUD) causes substantial harm. AUD affects 29 million individuals and causes more than 140,000 deaths annually in the U.S. alone. Individuals with AUD also often struggle ...
Jan 17, 2026
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Researchers revive an abandoned depression drug target using structurally novel NK1 receptor inhibitors
For decades, scientists have investigated the neurokinin-1 receptor (NK1R) as a potential target for treating major depressive disorder. Early studies suggested promise, but enthusiasm faded after clinical trials of drugs ...
Jan 14, 2026
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Near-atomic imaging reveals promising target for 'Brain on Fire' condition
Scientists have identified a promising target for treatment of a devastating autoimmune disease affecting the brain.
Jan 14, 2026
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Study finds non-hallucinogenic psilocybin neural receptor: A novel target for treating depression and anxiety
Psilocybin—the psychedelic compound that occurs naturally in certain "magic" mushroom species—has been shown in trials to provide long-term treatment for depression and anxiety. But the chemical's hallucinogenic effects can ...
Jan 13, 2026
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