MeSH tree: G04.043
Chromosomal instability is a common feature in many solid tumors and is associated with greater aggressiveness. For years, its main contribution to cancer was thought to be driving the evolution of tumor genomes, causing ...
Jun 6, 2026
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Researchers at The University of Texas MD Anderson Cancer Center have discovered a molecular pathway that drives certain stressed or aging cells to become abnormally active, causing inflammation inside blood vessel plaques. ...
Jun 4, 2026
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In response to stress or damage, cells undergo senescence and stop dividing. However, if senescent cells accumulate in tissues over the long term, chronic inflammation occurs and the risk of cancer increases. Researchers ...
Jun 3, 2026
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Molecular clocks that can provide accurate estimates of both molecular age and lifespan across multiple mammalian species and tissue types are presented in an article published in Nature this week. An analysis of more than ...
May 28, 2026
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With age, teeth get increasingly brittle and susceptible to damage from tooth decay, which can eventually lead to tooth loss. Teeth have an intrinsic capability to regenerate, a process that is driven by dental pulp stem ...
May 21, 2026
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People who carry the APOE2 version of the apolipoprotein E gene are more likely to live to advanced age and are partly protected against Alzheimer's disease, but scientists have struggled to explain why. A new study from ...
May 17, 2026
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A urine test developed by scientists at the University of Cambridge has moved a step closer to clinical use following new findings revealing it could do more than first thought. Originally designed to detect early signs of ...
May 13, 2026
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A newly discovered type of liver cell may hold clues for treating severe liver disease, according to a recent study from the University of Michigan Life Sciences Institute. The findings, published in the Journal of Clinical ...
May 4, 2026
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Chimeric antigen receptor (CAR) T-cell therapy is one of oncology's most powerful ideas: Harvest a cancer patient's own immune cells, genetically engineer them to recognize tumor cells, multiply them in a laboratory and reinject ...
Apr 29, 2026
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A new set of drugs exploit a recently revealed weakness in "zombie-like"—or senescent—cells that could lead to new treatments for cancer and age-associated diseases. The study from the MRC Laboratory of Medical Sciences (LMS) ...
Apr 24, 2026
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