FDA approves Opzelura for atopic dermatitis in children
The U.S. Food and Drug Administration has approved Opzelura cream 1.5% (ruxolitinib) for children ages 2 to 11 years with atopic dermatitis (AD).
Sep 29, 2025
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Chemical Actions and Uses: News and Research on Protein Kinase Inhibitors
MeSH tree: D27.505.519.389.755
Fresh hope for type 1 diabetes as daily pill that slows onset confirms promise at two-year follow-up
In 2023, the groundbreaking Australian BANDIT (Baricitinib in New Onset Type 1 Diabetes) trial reported that a daily pill of baricitinib, commonly prescribed for rheumatoid arthritis and alopecia, could safely preserve the ...
Sep 18, 2025
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Common autoimmune drug may help reverse immunotherapy-induced diabetes
A team of researchers at the UCLA Health Jonsson Comprehensive Cancer Center has identified a potential new strategy to prevent, and even reverse, immune checkpoint inhibitor–induced type 1 diabetes, a rare but life-threatening ...
Jul 8, 2025
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Common medicine for autoimmune diseases works on giant cell arteritis
A common medication already used for autoimmune diseases such as rheumatoid arthritis is effective for patients with giant cell arteritis, according to findings from a team at the Perelman School of Medicine at the University ...
Jun 25, 2025
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Novel therapy saves patient with severe heart inflammation
Acute myocarditis—sudden inflammation of the heart—causes mild symptoms in most cases, but about 10% of acute myocarditis cases can be sudden and severe, leading to cardiac arrhythmias, heart pump failure, or even death. ...
Jun 23, 2025
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Large study finds no significant overall cancer risk increase with JAK inhibitors in RA
Regulatory authorities issued precautionary recommendations following the ORAL Surveillance trial, which demonstrated an elevated risk of cancer with tofacitinib, compared to TNF inhibitors (TNFi).
Jun 12, 2025
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Benefits of early biologic treatment in psoriatic arthritis examined in studies
Two studies suggest there is no significant benefit of early biologics over standard step-up care with methotrexate, but these did not select for poor prognosis. The aim, therefore, of the SPEED trial (Severe Psoriatic arthritis—Early ...
Jun 11, 2025
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Report updates guidelines for pediatric atopic dermatitis management
In a clinical report published online May 19 in Pediatrics, the American Academy of Pediatrics presents updated guidance for the treatment of children with atopic dermatitis (AD).
May 19, 2025
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'Rogue' immune cells explain why a gluten-free diet fails in some celiac patients
Researchers at the Garvan Institute of Medical Research and UNSW Sydney have discovered why some people with celiac disease continue to suffer debilitating symptoms despite strictly avoiding gluten.
May 15, 2025
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JAK inhibitors show no increased cardiovascular risk in rheumatoid arthritis patients, large international study finds
An international research team led by Geneva University Hospital found no increase in cardiovascular events during the first two years of treatment with Janus kinase inhibitors (JAKi) compared to tumor necrosis factor inhibitors ...
