MeSH tree: G02.111.820
One of the main ways that the APOE4 gene variant, the biggest genetic risk factor for late-onset Alzheimer's disease, undermines brain circuit function is by disrupting the process of insulating neurons with a fatty sheath ...
22 hours ago
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The liver is organized into distinct zones in which liver cells perform different functions. The blood vessels of the liver play an important role in this spatial organization: the endothelial cells lining the vessels provide ...
Oct 7, 2026
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A protein known as p53 is, of all tumor suppressors in human cancer, the most frequently altered by gene mutations. When mutations cause it to be absent or nonfunctional, its loss can allow populations of mutant cells to ...
Oct 1, 2026
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Researchers at Weill Cornell Medicine and Hospital for Special Surgery have discovered the unspecialized stem cells that give rise to the body's tendons and ligaments, the tissues connecting muscles and bones.
Sep 7, 2026
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Triple-negative breast cancer (TNBC) is the most aggressive type of breast cancer. Chemotherapy before or after surgery remains the standard treatment regimen for stage I–III TNBC. Only a small portion of patients can benefit ...
Aug 31, 2026
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A new preclinical study has demonstrated that combining HER3-DXd with olaparib significantly improves treatment responses in lung cancer models. This combination therapy induces irreparable DNA damage in cancer cells while ...
Aug 24, 2026
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A research team led by Professor Ji Won Um of the Center for Synapse Diversity and Specificity, Department of Brain Sciences, DGIST, in collaboration with a team led by Professor Alice Ting at Stanford University, has developed ...
Aug 19, 2026
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The early period of life is a critical phase in which the immune system must learn to tolerate harmless environmental stimuli, such as food and microbes that normally live in and on the body, while remaining vigilant against ...
Aug 4, 2026
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The ability to adapt behavior flexibly to changing environments is a hallmark of intelligence. However, the biological mechanisms in the brain that are responsible for this cognitive flexibility remain poorly understood.
Jul 22, 2026
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Researchers at The University of Texas MD Anderson Cancer Center have discovered that an investigational epigenetic therapy remained effective in treatment-resistant acute myeloid leukemia (AML) by activating the Hippo pathway, ...
Jul 13, 2026
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