MeSH tree: C16.131.314.439
A multi-institutional study led by researchers at Children's Hospital of Philadelphia (CHOP) discovered for the first time that dietary interventions might prevent inflammatory symptoms associated with Hirschsprung disease, ...
9 hours ago
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The colon is about one and a half meters long and plays a vital role in moving waste through the body. In rare cases, it can become so stretched that it begins to lose its ability to work properly, like an elastic band that ...
Jun 14, 2026
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During development of the digestive system, a complex network of nerves forms around it, creating a "second brain"—the enteric nervous system (ENS)—which controls the movement of food and waste through the gut. But a combination ...
Dec 16, 2025
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A UCLA Health research team has helped define and characterize a rare bowel obstruction that affects premature infants, known as meconium-related obstruction of prematurity (MROP). Distinct from Hirschsprung disease and meconium ...
Sep 15, 2025
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Vanderbilt researchers, including those from the Vanderbilt Brain Institute, have made significant strides in understanding how the enteric nervous system—sometimes called the "brain" of the gut—forms and functions.
Sep 5, 2025
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Researchers at Karolinska Institutet have identified three types of nerve cells connected to the intestinal villi, suggesting that previously unknown neural networks regulate fluid balance in the gut.
May 29, 2025
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Wu Tsai Neurosciences Institute researchers have uncovered a previously unknown pattern of intestinal contractions in developing mouse embryos. The new findings shed light on the earliest development of the nervous system ...
Sep 5, 2024
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A new study led by researchers at UCL and the University of Sheffield, has demonstrated the potential of stem cell therapy to treat those with Hirschsprung disease.
Jun 27, 2024
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Wu Tsai Neuro Faculty Scholar Julia Kaltschmidt and MD/Ph.D. candidate Lori Dershowitz propose a novel theory that could transform our understanding of pediatric gastrointestinal (GI) motility disorders.
Apr 16, 2024
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A new surgical procedure successfully addresses a common lingering challenge—incontinence—faced by some families with young children who have undergone surgery for Hirschsprung disease. This first-of-its kind procedure was ...
Nov 14, 2022
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