MeSH tree: C16.320.400
There is no cure for the rare disease Hereditary Spastic Paraplegia (HSP), but researchers from Drexel University's College of Medicine and the UMass Chan Medical School have achieved proof-of-principle success with "silence ...
Dec 15, 2025
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Scientists found that messenger RNA (mRNA) molecules that carry genetic instructions to the far reaches of neurons in the brain tend to cluster together mostly because they are abundant, not because they move in coordinated ...
Dec 15, 2025
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Synaptic plasticity—the brain's ability to modify the connections between neurons to support learning—is one of the neural functions profoundly altered in Huntington's disease, with a direct impact on brain function. Researchers ...
Dec 10, 2025
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Friedreich's ataxia (FA) is a rare but devastating genetic disorder. Those with the condition are often diagnosed between 5 and 15 years of age and live only into their 30s or 40s. There is no widely approved treatment that ...
Dec 10, 2025
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Essential tremor (ET) is a common movement disorder affecting about 2% of the American population, and more than 20% of those over 90 years old. Despite its prevalence and decades of study, researchers don't know the precise ...
Dec 5, 2025
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Understanding the shape or morphology of neurons and mapping the tree-like branches via which they receive signals from other cells (i.e., dendrites) is a long-standing objective of neuroscience research. Ultimately, this ...
Some brain disorders are straightforward, such as the direct frontal lobe assault of a concussion or traumatic brain injury. Others, like Alexander disease, are akin to guerrilla warfare. Patients suffering from this genetic ...
Dec 1, 2025
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A team of researchers from the Germans Trias i Pujol Research Institute (IGTP) and Institut Català d'Oncologia (ICO) has studied alterations in the KRAS gene in colorectal cancer by combining genomic analyses with a systematic ...
Dec 1, 2025
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Whether speaking or swinging a bat, precise and adaptable timing of movement is essential for everyday behavior. Although we do not have sensory organs like eyes or a nose to sense time, we can keep time and control the timing ...
Nov 19, 2025
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A new, inexpensive urine test that measures two sugar alcohols, sorbitol and xylitol, is making it easier, faster, and far less expensive to identify a common inherited nerve disorder called SORD-related neuropathy. The test, ...
Nov 17, 2025
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