MeSH tree: C16.320.565.398
An editorial published in Brain Medicine raises the alarm about a previously overlooked threat to brain development and public health: the disruption of sterol biosynthesis by common prescription medications.
Apr 22, 2025
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In a preclinical study, researchers at Children's Hospital of Philadelphia (CHOP) demonstrated a novel gene therapy with potentially increased effectiveness and safety for the treatment of metachromatic leukodystrophy (MLD), ...
Mar 12, 2025
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Hereditary high cholesterol (FH) is the most common hereditary disease and, if left untreated, can lead to atherosclerosis, cardiovascular disease and, in the worst cases, blood clots.
Feb 5, 2025
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In two new papers, researchers from The Jackson Laboratory (JAX) report the successful use of two approaches—gene therapy and bone marrow transplantation—to alleviate symptoms of multiple sulfatase deficiency (MSD), an ultra-rare ...
Jan 29, 2025
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Researchers at Washington University School of Medicine in St. Louis have described the neurodegeneration that occurs in the nervous system of the bowel in Batten disease, a rare and fatal genetic condition. In their latest ...
Jan 15, 2025
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The U.S. government's premier research body has made an important discovery that could help create new drugs to lower "bad" cholesterol, and hopefully prevent heart attacks and stroke.
Dec 31, 2024
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National Institute of Health (NIH) scientists have made a significant breakthrough in understanding how "bad" cholesterol, known as low-density lipoprotein-cholesterol or LDL-C, builds up in the body. The researchers were ...
Dec 11, 2024
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Mayo Clinic's Center for Individualized Medicine has achieved a significant milestone with its Tapestry study, generating the clinic's largest-ever collection of exome data, which include genes that code for proteins—key ...
Dec 3, 2024
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The prevalence of high total cholesterol was 11.3% among U.S. adults from August 2021 to August 2023, according to a November data brief published by the National Center for Health Statistics.
Nov 20, 2024
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Nearly one in every 10 American adults is living with high levels of cholesterol in their arteries, according to the latest report from the U.S. Centers for Disease Control and Prevention.
Nov 20, 2024
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