MeSH tree: C06.130.120
Certain demographic, clinical, and genetic factors heighten the risk for extraintestinal manifestations (EIMs) with inflammatory bowel disease (IBD), according to a study published online March 13 in Gastroenterology.
Apr 17, 2024
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Using a novel methodology, researchers at The Hospital for Sick Children (SickKids) are the first in pediatric research to use data from an international real-world cohort to overcome the barriers associated with conducting ...
Feb 29, 2024
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28
Primary sclerosing cholangitis (PSC) is a severe and chronic liver disease. It affects men more than women, and most people who are diagnosed with PSC are between 30 and 40 years old.
Feb 16, 2024
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71
Research from the Gupta Lab provides important insights into the extrahepatic bile ducts. These bile ducts outside of the liver are a critical but poorly understood component of the human digestive system. The study, led ...
Dec 11, 2023
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The liver produces bile, which the intestine uses for digestion. For the transport of bile, the liver relies on a network of microscopic tubings, known as bile canaliculi, formed by liver cells called hepatocytes. When the ...
Sep 6, 2023
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25
A mechanism underlying several liver diseases involves bile produced in the liver that cannot be secreted into the intestine as intended. This leads to a backlog of bile, which can damage the liver tissue.
Jul 3, 2023
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72
A new research paper titled "Senescence and senotherapies in biliary atresia and biliary cirrhosis" has been published in Aging.
Jun 28, 2023
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63
Mayo Clinic researchers have identified a diverse range of environmental chemicals in human bile in patients with primary sclerosing cholangitis, a rare, chronic liver disease of the bile ducts. The study, published in Exposome, ...
May 24, 2023
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Alagille syndrome, a genetic disease estimated to affect 1 in 30,000 individuals, is caused by mutations in the gene JAG1 in most cases. The mutations affect multiple organs including the liver where it often results in cholestasis, ...
Apr 7, 2023
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66
Bile duct and gallbladder cancers develop in organs deep inside the body, making them difficult to detect.
Feb 1, 2023
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91
