MeSH tree: C06.130.120
A mechanism underlying several liver diseases involves bile produced in the liver that cannot be secreted into the intestine as intended. This leads to a backlog of bile, which can damage the liver tissue.
Jul 3, 2023
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72
A new research paper titled "Senescence and senotherapies in biliary atresia and biliary cirrhosis" has been published in Aging.
Jun 28, 2023
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62
Mayo Clinic researchers have identified a diverse range of environmental chemicals in human bile in patients with primary sclerosing cholangitis, a rare, chronic liver disease of the bile ducts. The study, published in Exposome, ...
May 24, 2023
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48
Alagille syndrome, a genetic disease estimated to affect 1 in 30,000 individuals, is caused by mutations in the gene JAG1 in most cases. The mutations affect multiple organs including the liver where it often results in cholestasis, ...
Apr 7, 2023
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66
Bile duct and gallbladder cancers develop in organs deep inside the body, making them difficult to detect.
Feb 1, 2023
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91
Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug. The study, ...
Jan 5, 2023
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59
Patients with cholestatic liver disease such as primary biliary cholangitis (PBC) can experience significant impairment of bile flow and may develop neurological symptoms including fatigue and cognitive decline. Little is ...
Dec 6, 2022
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41
Biliary atresia is a relatively rare childhood condition affecting the liver, with the potential to inflict hepatocellular damage or liver failure if left untreated. While the condition affects about 0.42 to 2.9 per 10,000 ...
Nov 16, 2022
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49
DEAR MAYO CLINIC: My husband is 45 and has lived with irritable bowel syndrome for many years. He was recently diagnosed with primary sclerosing cholangitis. Are these two conditions related? We were told a liver transplant ...
Jul 14, 2022
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403
