Amino acid glutamine is important for eye health, research finds
The retina places a large energy demand on the body, in part due to the activity of photoreceptors.
Aug 4, 2025
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Enzymes and Coenzymes: News and Research on Amidohydrolases
MeSH tree: D08.811.277.087
How scientists redesigned an effective cancer therapy to make it safer
University of Illinois Chicago scientists have redesigned a treatment for the most common pediatric leukemia to eliminate its severe side effects, like blood clots and liver damage. If approved, the new drug may be tolerated ...
Jan 31, 2025
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How a simple amino acid could shape immune response
A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response.
Jan 3, 2025
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Intestinal tuft cell expression changes with sleeping and eating cycles
A team of researchers from Carnegie Mellon University's Department of Biological Sciences and the University of Texas Southwestern Medical Center have uncovered how a subset of cells in the intestines change throughout the ...
Dec 17, 2024
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Gut microbe enzyme with surprising metabolic capabilities offers new therapeutic possibilities
To address childhood malnutrition—which affects 200 million children globally—researchers at Washington University School of Medicine in St. Louis have developed a therapeutic food that nourishes the collection of beneficial ...
Oct 24, 2024
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Strategy to combat breast cancer involves two-pronged attack on enzyme that 'feeds' tumor
A study led by Brazilian researchers and reported in an article published in the journal Nature Communications proposes that simultaneously targeting the enzyme glutaminase and the protein HuR, both of which are essential ...
Sep 27, 2024
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Age impacts pharmacogenomics and treatment outcomes for most common form of leukemia
Acute lymphoblastic leukemia (ALL) affects both children and adults, but children have better chances to be cured, with long-term survival rates of over 85% compared to 50%–75% in adults.
Aug 6, 2024
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Targeting vulnerability in B-cell development leads to novel drug combination for leukemia
Despite having an overall survival rate of 94%, B-cell acute lymphoblastic leukemia (B-ALL), the most common childhood cancer, can prove challenging to treat, with survival among relapsed or resistant cases falling between ...
Apr 8, 2024
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Review highlights beneficial interplay between caloric restriction, sirtuins and cardiovascular diseases
Cardiovascular disease (CVD) refers to a group of disorders affecting the heart and blood vessels and is a leading cause of death globally. Lifestyle factors have been linked to the incidence of CVD and the inclusion of an ...
Mar 28, 2024
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Filament formation enables cancer cells' glutamine addiction
Blocking the formation of filaments—multi-enzyme structures that fuel cancer activity—may offer new ways to control cancer cell proliferation, according to a new study led by Cornell researchers.
Mar 5, 2024
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