MeSH tree: G05.308.203.374
Since its discovery in 1998 and winning the Nobel Prize in 2006, ribonucleic acid (RNA) interference has become an invaluable tool for drugmakers to silence disease-causing genes. Nearly three decades later, drug makers have ...
Nov 13, 2024
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In Huntington's disease, the mutant huntingtin gene (HTT) mRNA is retained in the nucleus and forms insoluble clusters. A new study shows that short interfering RNA (siRNA), an oligonucleotide therapeutic strategy that reduces ...
Jul 22, 2024
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39
About one-third of adults have high blood pressure. Two-thirds of these have uncontrolled high blood pressure.
Jul 15, 2024
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30
Researchers at the University of Michigan Health Rogel Cancer Center are one step closer to understanding how pediatric DIPG tumors work.
Jun 13, 2024
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39
Scientists at UC Riverside have demonstrated a new, RNA-based vaccine strategy that is effective against any strain of a virus and can be used safely even by babies or the immunocompromised.
Apr 15, 2024
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203
Lung cancer cells survive better and exhibit less cell damage when exposed to cigarette smoke in cell culture experiments compared to non-cancerous lung cells. New research by a team of undergraduate students led by a Penn ...
Mar 6, 2024
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44
Researchers have newly identified a universal, essential biomarker for the childhood cancer neuroblastoma—and a potential new target for treatment.
Feb 28, 2024
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51
Alzheimer's disease, which is expected to have affected about 6.7 million patients in the U.S. in 2023, results in a substantial loss of brain cells. But the events that cause neuron death are poorly understood.
Jan 18, 2024
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382
A new editorial paper titled "DISE, an ancient anti-cancer mechanism that senses mutational load in cancerous cells?" has been published in Oncotarget.
Oct 3, 2023
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42
Developmental biologist Eric Lai, Ph.D., and his lab at Memorial Sloan Kettering Cancer Center (MSK) have been studying hotbeds of biological conflict, except instead of battles between outside invaders and internal defenders, ...
Aug 28, 2023
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