Researchers link cancer gene to Scottish island
People with grandparents from a remote Scottish island are more likely than the rest of the U.K. population to have a version of a gene that increases cancer risk.
Oct 24, 2024
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Genetic Phenomena: News and Research on Genes, BRCA2
MeSH tree: G05.360.340.024.340.375.249.105
Olaparib may be effective without hormone therapy for some men with biochemically recurrent prostate cancer
The anti-cancer drug olaparib may be effective in treating biochemically recurrent prostate cancer without accompanying hormone therapy for men who have mutations in genes such as BRCA2, according to results of a Phase II ...
Aug 22, 2024
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Genetic testing advances help women with high risk of breast cancer avoid surgery
Researchers are discovering new genes linked to breast cancer and refining evaluation of risk to help spare women from life-changing surgery.
Aug 20, 2024
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BRCA1 gene mutation may increase the risk of impaired fertility, study shows
People with a BRCA1 gene mutation, which increases breast and ovarian cancer risk, are also at increased risk of impaired fertility, Monash University-led research has confirmed in preclinical models and human tissue samples.
Jul 31, 2024
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Fanconi anemia: Researchers say brain tumors are fatal when there is a double gene mutation
Fanconi anemia (FA) is a rare hereditary cancer predisposition disease characterized by bone marrow failure as well as endocrine and physical abnormalities. A key clinical feature in those affected is a high risk of cancer. ...
Jun 3, 2024
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Scientists uncover a missing link between poor diet and higher cancer risk
A research team from the National University of Singapore (NUS) has unearthed new findings that may help explain the connection between cancer risk and poor diet, as well as common diseases like diabetes, which arise from ...
Apr 12, 2024
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Deciphering the male breast cancer genome
Male breast cancer has distinct alterations in the tumor genome that may suggest potential treatment targets, according to a study by Weill Cornell Medicine investigators. They have conducted the first whole genome sequencing ...
Mar 4, 2024
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BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula
A new research paper titled "Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health" has been published in Oncotarget.
Feb 28, 2024
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Drug found to extend survival in prostate cancer with genetic mutations
Men with hormone-resistant prostate cancer and specific genetic mutations who were treated with the PARP inhibitor drug olaparib survived longer than men treated with traditional hormone therapy, according to an analysis ...
Dec 7, 2023
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1 in 25 carries a genotype that is associated with a shortened lifespan, according to scientists
Scientists at deCODE genetics have published a study on actionable genotypes detected in the Icelandic population and their association with lifespan. The results of this study are among the things that have motivated the ...
Nov 8, 2023
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