Huge US study starts sharing gene findings with volunteers
More than 155,000 Americans who shared their DNA for science are about to learn something in return: Do they have some particularly worrisome genes?
Dec 13, 2022
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Genetic Phenomena: News and Research on Genes, BRCA2
MeSH tree: G05.360.340.024.340.415.400.105
Prostate cancer risk prediction algorithm could help targeted testing for men at greatest risk
Cambridge scientists have created a comprehensive tool for predicting an individual's risk of developing prostate cancer, which they say could help ensure that those men at greatest risk will receive the appropriate testing ...
Dec 9, 2022
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People with pancreatic cancer are living longer, thanks to improved approaches
A diagnosis of pancreatic cancer is almost synonymous with hopelessness. As the least survivable type of cancer, the perception is understandable. "As soon as patients were diagnosed, they were often told by their physician ...
Nov 30, 2022
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Team establishes a large collection of cholangiocarcinoma models for preclinical drug evaluation and biomarker discovery
Cholangiocarcinomas (CCAs) are a highly aggressive and diverse group of malignancies of the biliary tract that currently account for 15% of all liver cancers and approximately 3% of gastrointestinal tumors. While rare, the ...
Nov 29, 2022
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Blocking DNA production in cancer therapy by targeting the POLtheta enzyme
BRCA1 (BReast CAncer Gene 1), a key gene that becomes faulty in some instances, leading to breast and ovarian cancer, plays an important role in the body's DNA repair mechanisms. BRCA1, once mutated, can cause cancer to develop. ...
Nov 17, 2022
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Olaparib and adavosertib work best when given sequentially for DNA-damage response mutations in advanced tumors
Patients with cancers that are driven by certain mutations occurring in response to DNA damage can be safely treated with two drugs, olaparib and adavosertib, if they are given in sequence rather than concurrently.
Oct 27, 2022
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Identifying the underlying causes of ovarian cancer
Two new discoveries led by Cedars-Sinai Cancer investigators help improve the understanding of what drives the development of ovarian cancer and why some women's tumors do not respond to therapy.
Oct 10, 2022
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Pathogenic germline variants identified in patients with lung cancer
A total of 14.9 percent of patients with lung cancer have pathogenic germline variants (PGV), most of which are potentially clinically actionable, according to a study presented Aug. 16 as part of the American Society for ...
Aug 22, 2022
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9 common questions about genetic testing for cancer
Your genes play a role in nearly all areas of your health. A gene is like an instruction manual for your body that tells your body how to function, develop and stay healthy. People have about 20,000 genes in their bodies.
Jul 29, 2022
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Regular screening of people at high risk for pancreatic cancer pays off
Surveillance programs for people at high risk of developing pancreatic cancers can help detect precancerous conditions and cancers early, when they are most treatable, according to a new multicenter study directed by experts ...
Jul 13, 2022
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