MeSH tree: G05.365.590.175
Polyploidy is a state where a cell contains more copies of the genetic material than the usual "diploid" cell, which contains two copies. Polyploidy often occurs in human diseases and cancers, and its effect on cell fate ...
Oct 21, 2024
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Two complementary studies from the Faculty of Medical and Health Sciences at Tel Aviv University, in collaboration with the European Institute of Oncology in Milan, have extensively examined the characteristics of cells with ...
Sep 18, 2024
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Researchers from Karolinska Institutet have made a significant breakthrough in the study of childhood neuroblastoma, a type of cancer that begins before birth during the early stages of adrenal gland development.
Sep 11, 2024
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Cancer cells appear to hijack a genetic pathway involved in DNA repair to drive malignancy and overcome treatment, a study led by UT Southwestern Medical Center researchers shows. Their findings, published in Cell, explain ...
Sep 10, 2024
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Aneuploidy (the presence of an abnormal number of chromosomes) in embryos is a major cause of impaired embryo development, leading to conditions such as Down syndrome, as well as to pregnancy loss. The transfer of such embryos ...
Jun 3, 2024
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Blood stem cells from healthy people carry major chromosomal alterations, suggesting we are all genetic mosaics, according to a new study from EMBL and the Max Delbrück Center.
May 28, 2024
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Congenital heart disease (CHD) includes a variety of structural malformations affecting the heart and blood vessels. With growing understanding of the molecular processes involved in heart development, genetic variants have ...
May 16, 2024
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Gastric cancer (GC) ranks as the fifth-most common and fourth-deadliest cancer worldwide, presenting significant health challenges, particularly in China, where it is most prevalent and accounts for nearly half of newly diagnosed ...
May 7, 2024
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A study in mice suggests how chromosome inactivation may protect girls from a type of autism disorder inherited from their father's X chromosome.
Apr 30, 2024
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Scientists have unraveled the mechanisms of the cyclic guanosine monophosphate-adenosine monophosphate synthase-stimulator of interferon genes (cGAS-STING) signaling pathway activated by micronuclei, as well as its significant ...
Apr 9, 2024
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