MeSH tree: G05.728.615
The race to complete the human pangenome—which comprises all genetic information across the human species—has been underway since 2022, when the first complete reference human genome sequence was released by the international ...
Jun 10, 2026
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In a new Dartmouth Cancer Center (DCC) study led by clinical researcher Tyler J. Curiel, MD, MPH, FACP, investigators found that the FDA-approved blood pressure drug telmisartan can significantly enhance the cancer-killing ...
Mar 25, 2026
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One of the biggest challenges in cancer treatment is chemoresistance: Tumors that initially respond well to chemotherapy become resistant over time. When that happens, treatment options are often limited.
Oct 30, 2025
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In a new study published in the Journal of Hepatology, researchers from the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) show that only 15–20% of hepatocytes in newborn mice—dubbed clonogenic hepatocytes—are ...
Aug 28, 2025
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Scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have made one of the most important discoveries to date in the study and treatment of BRCA1-deficient cancers and drug resistance.
Jun 10, 2025
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Research by UMass Chan Medical School scientists Sharon Cantor, Ph.D., and Jenna M. Whalen, Ph.D., poses a new explanation for how cancer-fighting drugs attack and destroy BRCA1 and BRCA2 tumor cells.
Feb 25, 2025
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Gene editing is already being used to treat a handful of rare genetic diseases; however, most therapies involve breaking or inactivating genes. Precisely fixing disease-causing mutations is far more difficult. This is especially ...
Feb 12, 2025
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A new study led by The University of Texas Health Science Center at San Antonio (UT Health San Antonio) is shedding light on a novel role of breast cancer gene 1 (BRCA1) in tumor suppression.
Oct 25, 2024
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Researchers at The Institute of Cancer Research, London, have increased our understanding of how a cancer drug called a PARP inhibitor stops working in women with breast cancer that has spread. This research could ultimately ...
May 8, 2024
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Researchers at Baylor College of Medicine have identified a small molecule named 5D4 that can suppress the growth of breast and ovarian cancers in animal models. 5D4 works by binding to TopBP1 protein in cancer cells, disrupting ...
Oct 25, 2023
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