Why do I bruise so easily? Could it be something serious?
After a bump, we can expect a bruise. But what if we find ourselves bruising without any noticeable cause? What might be behind it? Should we worry?
Oct 20, 2023
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Hemic and Lymphatic Diseases: News and Research on Blood Coagulation Disorders, Inherited
MeSH tree: C15.378.100.100
Researchers uncover mysteries behind immune response to hemophilia A treatment
Patients with the genetic disorder hemophilia A receive factor VIII protein replacement treatments to replenish this clotting protein in their blood, thus preventing dangerous bleeding. Unfortunately, about 30% of these patients ...
Aug 14, 2023
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FDA approves first gene therapy for severe hemophilia A
The U.S. Food and Drug Administration on Thursday approved a costly single-dose gene therapy for patients with severe hemophilia A, a life-threatening hereditary bleeding disorder.
Jul 3, 2023
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This panel will decide whose medicine to make affordable. Its choice will be tricky.
Catherine Reitzel's multiple sclerosis medication costs nearly $100,000 a year. Kris Garcia relies on a drug for a blood-clotting disorder that runs $10,000 for a three-day supply. And Mariana Marquez-Farmer would likely ...
May 31, 2023
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Gene therapy beneficial for patients with hemophilia B
For patients with hemophilia B, one infusion of adeno-associated virus 5 (AAV5) vector expressing the Padua factor IX variant (etranacogene dezaparvovec) is noninferior and superior to prophylaxis with factor IX, according ...
Mar 3, 2023
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Benefits of valoctocogene roxaparvovec persist in hemophilia A
For patients with hemophilia A, factor VIII activity and bleeding reduction persist at two years after gene transfer with valoctocogene roxaparvovec, which delivers a B-domain-deleted factor VIII coding sequence with an adeno-associated ...
Mar 3, 2023
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Immune reactions identified that may cause antibody development in hemophilia A cases
In hemophilia A cases, the body either partially or completely lacks the blood coagulation factor VIII (FVIII), or the factor is formed incorrectly. Patients usually receive FVIII that comes from donor blood or is produced ...
Feb 7, 2023
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Researchers trial potential hemophilia treatment
A global study involving McMaster University researchers has trialed a potential new treatment that could be a game-changer for people living with hemophilia A, a life-threatening genetic blood disorder.
Jan 26, 2023
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Liver cancer study encourages caution with certain gene therapies
Research led by Randal J. Kaufman, Ph.D., has found that misfolded proteins in liver cells contribute to the development of liver cancer, shedding new light on the mysterious origins of one of the world's deadliest diseases. ...
Dec 7, 2022
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A gene therapy for hemophilia that costs $3.5 million gets FDA approval
People with one form of the genetic blood disorder hemophilia now have a one-time treatment with a $3.5 million price tag.
Nov 23, 2022
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