MeSH tree: C15.378.100
For patients with hemophilia A, factor VIII activity and bleeding reduction persist at two years after gene transfer with valoctocogene roxaparvovec, which delivers a B-domain-deleted factor VIII coding sequence with an adeno-associated ...
Mar 3, 2023
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In hemophilia A cases, the body either partially or completely lacks the blood coagulation factor VIII (FVIII), or the factor is formed incorrectly. Patients usually receive FVIII that comes from donor blood or is produced ...
Feb 7, 2023
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A global study involving McMaster University researchers has trialed a potential new treatment that could be a game-changer for people living with hemophilia A, a life-threatening genetic blood disorder.
Jan 26, 2023
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Independent risk factors for congenital hearing loss have been identified in newborns with congenital cytomegalovirus (cCMV) infection, according to a study published online Dec. 29 in JAMA Otolaryngology-Head & Neck Surgery.
Dec 30, 2022
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Research led by Randal J. Kaufman, Ph.D., has found that misfolded proteins in liver cells contribute to the development of liver cancer, shedding new light on the mysterious origins of one of the world's deadliest diseases. ...
Dec 7, 2022
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People with one form of the genetic blood disorder hemophilia now have a one-time treatment with a $3.5 million price tag.
Nov 23, 2022
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Immune responses against Factor VIII, which is used to treat hemophilia A (bleeding disorder), are influenced by the microenvironment of antigen presenting cells. This is the result of a scientific study conducted in cooperation ...
Nov 22, 2022
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Hemophilia A is the most common severe form of hemophilia. It almost exclusively affects males. The disease can usually be treated well, but not for all sufferers. A study at the University of Bonn has now elucidated an important ...
Oct 26, 2022
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There are numerous severe, difficult-to-treat monogenetic diseases that are caused by a defect in a single gene—also in the liver. These include the blood coagulation disorders hemophilia A or B or the metabolic disease phenylketonuria. ...
Oct 26, 2022
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In a clinical report issued by the American Academy of Pediatrics and published online Sept. 19 in Pediatrics, recommendations are presented to help guide pediatricians and other clinicians in the assessment of bleeding disorders ...
Oct 3, 2022
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