MeSH tree: D03.383.129.308.240
Scientists at the Terasaki Institute for Biomedical Innovation (TIBI), led by Dr. Vadim Jucaud (Assistant Professor), have engineered a novel multi-cellular 3D glioblastoma (GBM) in vitro model that mimics the biomechanical ...
May 27, 2025
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New research from SAHMRI and Flinders University has shed light on how the decades-old antipsychotic drug, trifluoperazine (TFP), works against glioblastoma (GBM), the most aggressive form of brain cancer.
Apr 30, 2025
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Researchers at Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, report in Nature Communications on how the targeted suppression of lysosome function may lead to brain cancer therapy.
Apr 9, 2025
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Glioblastoma is the most aggressive and most common malignant brain cancer in adults. It is currently treated with surgery, followed by radiation and chemotherapy. The prognosis is poor even with treatment. A challenge in ...
Feb 20, 2025
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In spite of intensive research, glioblastoma remains one of the most lethal types of brain cancer. Temozolomide (TMZ) is used as the front-line medicine in its treatment.
Dec 19, 2024
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A simple change to the chemotherapy regimen for people with Hodgkin lymphoma could reduce the long-term health impacts that can result from treatment, according to researchers in Cambridge. The findings could lead to the ...
Dec 12, 2024
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Both radiation and temozolomide, a generic chemotherapy treatment in pill form, have meaningful single-modality anti-tumor activity against slow-growing, low-grade gliomas. The randomized phase 3 trial E3F05 by the ECOG-ACRIN ...
Nov 25, 2024
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A study led by Dr. Monika E. Hegi, MD, Ph.D. and European Organization for Research and Treatment of Cancer (EORTC) headquarters team (Felix Oppong Msc, Dr. Thierry Gorlia, Ph.D.) reveals that elderly glioblastoma patients ...
Oct 9, 2024
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Glioblastoma is one of the most serious brain diseases known. More than 45% of brain cancers are gliomas. Only half of glioblastoma patients respond to the FDA-approved chemotherapy temozolomide (TMZ). Even for those patients, ...
Sep 30, 2024
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A new approach to treating the most malignant type of brain cancer—glioblastoma—has shown strong promise in pre-clinical settings, raising hopes of increasing current average survival rates beyond 18 months.
Jul 9, 2024
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