MeSH tree: D03.383.742.680.245
When people develop myelodysplastic neoplasms (MDS), the healthy maturation of blood cells is impaired. Severe forms, known as higher-risk MDS, are characterized by rapid progression, severe symptoms and often a transition ...
Jan 22, 2024
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Endocrine resistance—a major cause of breast cancer deaths—can be underpinned by an epigenetic change called DNA methylation, researchers at the Garvan Institute of Medical Research have discovered. The team successfully ...
Jan 9, 2024
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The PrEPVacc HIV prevention study of experimental vaccine regimens and a new form of oral pre-exposure prophylaxis (PrEP) running in East and Southern Africa among 1,500 volunteer participants has stopped further vaccinations ...
Dec 7, 2023
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Biliary tract cancers (BTCs) including cholangiocarcinoma (CCA) and gallbladder cancer (GBC) are becoming more prevalent globally. An effective chemotherapeutic agent for the treatment of BTCs is gemcitabine. Other novel ...
Nov 30, 2023
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Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant ...
Nov 16, 2023
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Epigenetic changes can cause prostate cancer to resist treatment by switching genes on or off. One epigenetic mechanism tags genes with DNA methylation marks. This process is mediated by molecules called DNA methyltransferases. ...
Nov 15, 2023
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Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer. Researchers from VCU Massey Comprehensive Cancer Center and the VCU Institute ...
Nov 10, 2023
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Epigenetically active drugs enable the cell to read parts oft he genome that were previously blocked and inaccessible. This leads to the formation of new mRNA transcripts and also new proteins, as scientists from the German ...
Oct 24, 2023
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A new injectable solution that self-assembles into a gel under the right conditions could help manage HIV unlike any currently available methods, researchers have found.
Sep 25, 2023
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To give cancer treatments the greatest possible chance of success, patients are often treated with multiple drugs that attack the cancer using different mechanisms. A team of researchers has now combined three highly potent ...
Sep 19, 2023
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