Chinese company may help ease U.S. shortage of cancer drug
With the United States facing a high number of drug shortages, a Chinese company may help to boost the supply of one in particular, the chemotherapy agent cisplatin.
Jun 5, 2023
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Inorganic Chemicals: News and Research on Platinum Compounds
MeSH tree: D01.710
Circumventing the renal toxicity associated with cisplatin treatment
Cisplatin is widely used as a chemotherapeutic agent for the treatment of various solid tumors, including bladder, ovarian, and esophageal tumors. However, on metabolism by an enzyme called "cysteine conjugate beta-lyase ...
May 23, 2023
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'Never did I imagine that I would have to ration chemotherapy'
Nationwide shortages of two dozen chemotherapy drugs are leading to rationing and delays in treatment for cancer patients, local and national authorities say.
May 22, 2023
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Research predicts cancer patients' response to chemotherapy agent cisplatin
Researchers at Cleveland Clinic have taken an important step in predicting which treatment will work for individual cancer patients. Using a gene signature developed from cell lines and human tissue, the research team demonstrated ...
Apr 20, 2023
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Fibroblast inhibitors assist anti-cancer drugs to suppress cancer growth
Fibroblasts build and maintain the extracellular matrix, or physical scaffolding for cells, in the connective tissues within the body. It is believed that cancerous tumors can recruit nearby fibroblasts and use them to promote ...
Mar 28, 2023
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Clinical study: Treatment improves outcomes for women with locally advanced vulvar cancer
Results from the NRG Oncology Phase II NRG-GOG-0279 clinical study indicate that women with locally advanced squamous cell carcinoma of the vulva who received gemcitabine concurrently with cisplatin and intensity-modulated ...
Mar 27, 2023
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Studies reveal biosafety effects of moderate and high static magnetic fields
In three recent studies, Chinese researchers have delayed natural aging in healthy mice by continuous exposure to quasi-homogeneous static magnetic fields (SMFs) of moderate intensity, mitigated kidney damage induced by the ...
Feb 27, 2023
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A potential therapy to reduce the side effects of chemotherapy
Cisplatin is a chemotherapy indicated to fight tumors in many types of cancer. However, it does have major side effects—especially kidney toxicity, that can lead to acute kidney failure.
Nov 15, 2022
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Study identifies new gene that can increase chemotherapeutic response in medulloblastomas
An international team led by the Department of Neurosurgery, Niigata University, has identified a new gene called Schlafen11 (SLFN11) whose expression is tightly correlated with the response to chemotherapy in medulloblastomas, ...
Nov 8, 2022
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Combination treatment shows promise in patients with chemotherapy-resistant urothelial cancer
A combination of two types of cancer-fighting treatments—the immunotherapy agent pembrolizumab and a nanoparticle-bound form of the chemotherapy drug paclitaxel—may provide an urgently needed new treatment approach for patients ...
Nov 3, 2022
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