MeSH tree: E05.478.605
As we age, our ability to maintain healthy blood and a strong immune system gradually declines, largely because hematopoietic stem cells (HSCs), the cells responsible for producing all blood cell types, begin to lose their ...
Apr 16, 2026
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The human genome contains approximately 1,600 types of transcription factors responsible for regulating gene activity across more than 400 tissue and cell types. Chromatin immunoprecipitation sequencing (ChIP-seq) is a key ...
Dec 15, 2025
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The number of colorectal cancer cases in people under 50 is rising worldwide, especially in high-income countries. Possible causes include Western diets, obesity, lack of exercise, and the use of antibiotics, especially in ...
Jul 2, 2025
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Researchers from Children's Hospital of Philadelphia (CHOP) and the Perelman School of Medicine at the University of Pennsylvania (Penn Medicine) have successfully employed an algorithm to identify potential mutations which ...
Apr 17, 2025
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Structural Genomics Consortium researchers at The Neuro (Montreal Neurological Institute-Hospital) of McGill University, in collaboration with scientists from 11 major antibody manufacturers representing approximately 80% ...
Dec 18, 2024
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Microglia are the immune system's front-line enforcers in the brain. They are cells that patrol the brain and destroy anything harmful that they encounter, from invading bacteria to cellular debris. They also remove plaques ...
Aug 16, 2024
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Scientists have generated a comprehensive map of the gene targets regulated by the transcription factors HNF4A and HNF1A in human pancreatic beta cells and liver cells. Published in the journal Nature Communications, the ...
Jun 26, 2024
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Transcription factors (TFs) are proteins that bind to specific DNA sequences, regulating the transcription of genetic information from DNA to messenger RNA (mRNA). These proteins play a pivotal role in the regulation of gene ...
Scientists believe a buildup of the brain protein amyloid beta plays a key role in the death of neurons, which can lead to Alzheimer's disease. Although most people develop some amyloid beta brain proteins as they age, researchers ...
Dec 11, 2023
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UT Southwestern Medical Center researchers have mapped gene control elements in specialized cardiac cells responsible for coordinating heartbeats. The findings of the genome exploration study, published in The Journal of ...
Feb 13, 2023
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