New clues reveal how gestational diabetes affects offspring
Gestational diabetes can cause a multitude of complications in the offspring, but to date, the reasons are incompletely understood.
Nov 18, 2025
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16
Metabolism: News and Research on RNA Splicing
MeSH tree: G03.839.700
NAD⁺ restores memory in Alzheimer's disease models by correcting RNA errors
Alzheimer's disease (AD), the leading cause of dementia, affects nearly 40 million individuals globally, resulting in a gradual loss of memory and independence. Despite extensive research over the past decades, no treatments ...
Nov 10, 2025
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800
Living brain tissue reveals unique RNA and protein patterns missed in postmortem studies
Two new research papers from the Living Brain Project at Mount Sinai present what is, by several metrics, the largest investigation ever performed of the biology of the living human brain. The papers present unequivocal evidence ...
Oct 15, 2025
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65
RNA isoform atlas may improve understanding of cardiovascular disease
Northwestern Medicine scientists have developed a comprehensive atlas of genetic coding sequences in both healthy adult hearts and those with heart failure, a resource that has the potential to improve the understanding of ...
Sep 29, 2025
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19
Chronic alcohol use halts liver cell regeneration, new study finds
Excessive alcohol consumption can disrupt the liver's unique regenerative abilities by trapping cells in limbo between their functional and regenerative states, even after a patient stops drinking, researchers at University ...
Sep 10, 2025
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1290
Study uncovers key proteins that keep the heart beating properly
A groundbreaking new study led by researchers at the Masonic Medical Research Institute (MMRI) has identified that two closely related proteins, RBPMS and RBPMS2, act in tandem to protect the heart's ability to process the ...
Aug 29, 2025
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21
Activated immune cells reveal hidden drivers of autoimmune diseases
By stimulating macrophages—a type of white blood cell—with biological factors that mimic infection, researchers have uncovered genetic drivers of complex diseases such as inflammatory bowel disease (IBD), in one of the largest ...
Aug 27, 2025
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25
Scrambled RNA nudges millions of people towards type 2 diabetes, research reveals
Mutations in a single gene, HNF1A, are known to cause MODY3, a rare, early-onset form of diabetes. Smaller-scale mutations in the very same gene are also common and quietly nudge millions of people toward type 2 diabetes. ...
Aug 6, 2025
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41
Genetic cause for rare childhood brain developmental disorder found
University of Otago–Ōtākou Whakaihu Waka has led international research uncovering a new genetic cause for a rare developmental disorder that profoundly impacts brain growth and function in children.
Jun 23, 2025
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How the ELAV protein shapes the brain's unique circular RNA landscape
Deep within our nerve cells, a molecule is at work that has no beginning and no end. Instead of a straight chain, as is common for most RNA strands, it forms a closed loop. Known as circular RNAs (circRNAs), these molecules ...
Jun 10, 2025
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