MeSH tree: C04.557.450.565.575.650
Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers. Now, a new study suggests that blocking a key protein, p300, may force damaged cancer cells into a state ...
Feb 6, 2026
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When surgeons remove an aggressive bone tumor from the pelvis, saving a patient's life can mean sacrificing a large portion of the spine and hip. Putting that fragile structure back together in a way that will let the patient ...
Dec 18, 2025
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University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled order, allowing cancer ...
Dec 11, 2025
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Peripheral afferent neurons—nerves that send signals from all areas of the body to the central nervous system (brain and spinal cord)—are known to infiltrate and grow within malignant bone tumors called osteosarcomas, often ...
Oct 28, 2025
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Ewing sarcoma is one of the most common bone cancers seen in children, and if it spreads, it can be deadly. One study found that under a quarter of children with multi-metastatic Ewing sarcoma survived five years after their ...
Oct 23, 2025
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A research team at the Seville Biomedical Institute (IBis) has identified a new molecular mechanism that explains the high sensitivity of Ewing sarcoma (an aggressive bone cancer that mainly affects children and adolescents) ...
Oct 16, 2025
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Researchers at Cleveland Clinic Children's have helped identify a previously unknown gene that increases the risk of developing osteosarcoma, the most common type of malignant bone tumor in children and young adults.
Oct 9, 2025
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Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate conformation. Much of this processing occurs in the endoplasmic reticulum (ER) of every cell.
Sep 25, 2025
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A research project has reached an important milestone: the first treatment of an animal tumor with radioactive ion beams has been demonstrated and published in Nature Physics.
Aug 19, 2025
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Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers' ability to detect complex genetic alterations in cancer genomes. However, the complex structure ...
May 29, 2025
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