MeSH tree: C04.557.450.565
A research team at the Seville Biomedical Institute (IBis) has identified a new molecular mechanism that explains the high sensitivity of Ewing sarcoma (an aggressive bone cancer that mainly affects children and adolescents) ...
Oct 16, 2025
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Researchers at Cleveland Clinic Children's have helped identify a previously unknown gene that increases the risk of developing osteosarcoma, the most common type of malignant bone tumor in children and young adults.
Oct 9, 2025
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Before a chain of amino acids can become an active and useful protein, it must be processed and folded into the appropriate conformation. Much of this processing occurs in the endoplasmic reticulum (ER) of every cell.
Sep 25, 2025
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A novel targeted radiation approach for a rare form of malignant tumor—the solitary fibrous tumor (SFT)—has shown significant success, achieving a near-complete response in three patients. The therapy significantly reduced ...
Sep 17, 2025
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In the sport of sumo, a bout most commonly ends when one competitor is pushed or thrown outside of a ring of straw bales partially buried in clay. New research shows that using a drug as a blocker to outcompete the SUMO2 ...
Sep 4, 2025
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Gastrointestinal stromal tumors (GISTs) are the most common type of sarcoma, often driven by mutations in the KIT or PDGFRA genes. Tyrosine kinase inhibitors (TKIs) like imatinib have been the cornerstone of treatment, but ...
Aug 27, 2025
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A research project has reached an important milestone: the first treatment of an animal tumor with radioactive ion beams has been demonstrated and published in Nature Physics.
Aug 19, 2025
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A new study delving into the genetic drivers of a rare and aggressive childhood cancer called Malignant Peripheral Nerve Sheath Tumor (MPNST) has revealed metabolic frailties in the cancer cells that might be exploited to ...
Aug 19, 2025
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Inspired by advances in cancer therapy, a team at the Buck Institute has engineered immune cells equipped with specialized targeting devices called chimeric antigen receptors (CARs) that can distinguish and respond to tau ...
Jun 12, 2025
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Long-read sequencing technologies analyze long, continuous stretches of DNA. These methods have the potential to improve researchers' ability to detect complex genetic alterations in cancer genomes. However, the complex structure ...
May 29, 2025
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