MeSH tree: C04.557.470.670.590
Children with a rare form of cancer called neuroblastoma which hasn't responded to initial treatment or that has relapsed may benefit from adding antibody treatment to usual chemotherapy, according to new results from a clinical ...
Dec 12, 2025
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A discovery from Australian researchers could lead to better treatment for children with neuroblastoma, a cancer that currently claims 9 out of 10 young patients who experience recurrence. The team at the Garvan Institute ...
Nov 28, 2025
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Neuroblastoma remains one of the deadliest childhood malignancies, accounting for a disproportionate number of pediatric cancer deaths worldwide.
Nov 13, 2025
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The malignant pediatric brain tumor medulloblastoma is driven by proteins deep within the cancer cells, for which there are often no effective drugs available. Researchers at Uppsala University have identified a new genetic ...
Nov 10, 2025
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By analyzing data from three clinical trials treating children with the brain tumor medulloblastoma, scientists at St. Jude Children's Research Hospital have designed an approach to safely reduce therapy, thereby lowering ...
Nov 5, 2025
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Neuroblastoma is a type of cancer that affects the sympathetic nervous system in young children and is often difficult to treat, especially when the tumor cells carry multiple copies of the MYCN gene.
Oct 22, 2025
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Researchers at Children's Hospital of Philadelphia (CHOP) found that combining a specialized diet with an approved medication interrupts the growth of high-risk neuroblastoma, a deadly pediatric cancer, by reprogramming tumor ...
Sep 25, 2025
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Gene expression governs whether neuroblastoma tumor cells exist in either the adrenergic (differentiated and sensitive to treatment) or mesenchymal (less differentiated and therapy-resistant) cell state. Tumors may switch ...
Sep 17, 2025
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Researchers at Children's Hospital of Philadelphia (CHOP) unveiled a novel antibody-drug conjugate (ADC) that shows striking efficacy against cancers that express the anaplastic lymphoma kinase (ALK) protein on the cancer ...
Sep 16, 2025
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New research has uncovered how cerebrospinal fluid dynamics in the brain play an important role in driving the spread of medulloblastoma, the most common malignant brain tumor in children.
Sep 4, 2025
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