Gene editing disrupts Huntington's mutation in mice
Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and Friedreich's ataxia.
May 27, 2025
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Nervous System Diseases: News and Research on Cerebellar Diseases
MeSH tree: C10.228.140.252
Genome mapping of Brazil's diverse population uncovers new variants linked to health
For the first time, an international study has deciphered the genome of the population of Brazil. Published in the journal Science, the research includes the African, Native American, and European ancestries making up this ...
May 15, 2025
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Compact gene circuit uses microRNA to fine-tune therapy for rare diseases
Many diseases are caused by a missing or defective copy of a single gene. For decades, scientists have been working on gene therapy treatments that could cure such diseases by delivering a new copy of the missing genes to ...
Apr 28, 2025
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Rare diseases often go undiagnosed or untreated in parts of Africa. A project seeks to change that
Ndeye Lam visits the cemetery often, praying and gently touching the seashells laid out across her daughter's gravesite.
Apr 27, 2025
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How the cerebellum controls tongue movements to grab food
By studying the skilled movements of marmoset tongues, researchers have discovered that Purkinje cells (P-cells) in a brain region called the cerebellum signal to stop protrusion as the tongue approaches its target, according ...
Apr 10, 2025
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DeepCeres: AI-driven software redefines cerebellum research with detailed imaging
A team of researchers from the Universitat Politècnica de València (UPV) and the French National Center for Scientific Research (CNRS) has developed the world's most advanced software to study the human cerebellum using high-resolution ...
Mar 20, 2025
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Unlocking a common cause of ataxia: A step toward effective treatment
Cerebellar rhythm loss due to climbing fiber regression is a shared pathophysiology of motor deficits across cerebellar ataxias. Cerebellar ataxias are a group of genetic and non-genetic disorders that currently have no effective ...
Mar 11, 2025
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Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits
A team has conducted a trial on the efficacy and safety of L-arginine in treating spinocerebellar ataxia type 6 (SCA6).
Dec 4, 2024
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New type of cerebellar ataxia discovered: How the immune system destroys the cerebellum
Cerebellar ataxia is a neurological disorder of the cerebellum. This important area at the back of the brain acts as a conductor, so to speak, coordinating our movements and keeping us in balance.
May 30, 2024
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Study shows that the cerebellum is involved in processing emotions, with implications for ataxia care
For a long time, the fact that the cerebellum plays an important role in regulating our emotions—such as when processing fear—has been ignored. Professor Melanie Mark from Ruhr-University Bochum and Professor Dagmar Timmann ...
May 7, 2024
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