How a 'speech gene' could help treat Huntington's
In fatal genetic diseases like Huntington's and spinocerebellar ataxia, proteins develop long stretches of repeating letters that are prone to sticking together like Velcro.
Sep 24, 2025
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Nervous System Diseases: News and Research on Spinocerebellar Degenerations
MeSH tree: C10.574.500.825
Gene editing disrupts Huntington's mutation in mice
Broad Institute researchers have developed a way to edit the genetic sequences at the root of Huntington's disease and Friedreich's ataxia.
May 27, 2025
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Genome mapping of Brazil's diverse population uncovers new variants linked to health
For the first time, an international study has deciphered the genome of the population of Brazil. Published in the journal Science, the research includes the African, Native American, and European ancestries making up this ...
May 15, 2025
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Compact gene circuit uses microRNA to fine-tune therapy for rare diseases
Many diseases are caused by a missing or defective copy of a single gene. For decades, scientists have been working on gene therapy treatments that could cure such diseases by delivering a new copy of the missing genes to ...
Apr 28, 2025
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Rare diseases often go undiagnosed or untreated in parts of Africa. A project seeks to change that
Ndeye Lam visits the cemetery often, praying and gently touching the seashells laid out across her daughter's gravesite.
Apr 27, 2025
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Clinical trial suggests new drug candidate for spinocerebellar ataxia may offer certain therapeutic benefits
A team has conducted a trial on the efficacy and safety of L-arginine in treating spinocerebellar ataxia type 6 (SCA6).
Dec 4, 2024
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Study shows that the cerebellum is involved in processing emotions, with implications for ataxia care
For a long time, the fact that the cerebellum plays an important role in regulating our emotions—such as when processing fear—has been ignored. Professor Melanie Mark from Ruhr-University Bochum and Professor Dagmar Timmann ...
May 7, 2024
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A promising discovery in a rare neurodegenerative disease
Imagine being middle aged and starting to feel that you are off balance a lot and that you are having a hard time coordinating your movements. Those are among the symptoms of Spinocerebellar ataxia type 6, known as SCA6, ...
Mar 27, 2024
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Scientists tame biological trigger of deadly Huntington's disease
Huntington's disease causes involuntary movements and dementia, has no cure, and is fatal. For the first time, UC Riverside scientists have shown they can slow its progression in flies and worms, opening the door to human ...
Nov 8, 2023
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Study uncovers potential new source of genetic mutations that cause neurodegenerative disease
Scientists have discovered an additional potential cause of the genetic mutations that result in rare conditions such as Huntington's disease (HD).
Aug 17, 2023
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