MeSH tree: D13.570.230
Patients with leptomeningeal metastasis (LM) have historically had few treatment options. Now, researchers from The University of Texas MD Anderson Cancer Center have found a combination of targeted therapies, tucatinib and ...
Mar 18, 2026
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Research led by the Max Planck Institute for Biology of Aging in Cologne reports that misincorporation of ribonucleotides into mitochondrial DNA (mtDNA) initiates an inflammatory cascade.
JoEllen Zembruski-Ruple, while in the care of New York City's renowned Memorial Sloan Kettering Cancer Center, swallowed the first three chemotherapy pills to treat her squamous cell carcinoma on Jan. 29, her family members ...
Jun 9, 2025
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An inexpensive, long-approved HIV drug can improve vision in patients with a blinding complication of diabetes more effectively and at a much lower cost than many existing treatments, an initial clinical trial suggests. Further, ...
May 27, 2025
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Researchers at the Icahn School of Medicine at Mount Sinai have developed a powerful computational tool, named iDOMO, to improve the prediction of drug synergy and accelerate the development of combination therapies for complex ...
Feb 20, 2025
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Researchers at Washington University School of Medicine in St. Louis have developed a way to capture the effects of aging in the development of Alzheimer's disease. They devised a method to study aged neurons in the lab without ...
Aug 1, 2024
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A new study has found that increased coronary vessel wall thickness is significantly associated with impaired diastolic function in asymptomatic, middle-aged individuals living with HIV. The study is published in Radiology: ...
Apr 4, 2024
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In a Pittsburgh hospital in the early 1980s, Charles Rinaldo saw a young, previously healthy gay man critically ill with a virus usually only seen in weakened immune systems.
Apr 1, 2024
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One January morning in 2021, Carol Rosen took a standard treatment for metastatic breast cancer. Three gruesome weeks later, she died in excruciating pain from the very drug meant to prolong her life.
Mar 29, 2024
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Multiple sclerosis (MS) is a disease that looks different in everyone who has it—and you may know more people who have it than you think.
Mar 5, 2024
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